E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome

Jayant Chauhan, Bhavesh Patel, Chirag Parekh.

Abstract
Background: Asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome defined as a syndrome characterized by persistent airflow limitation with several features usually associated with asthma and several features usually associated with COPD. This overlap makes the difference between COPD and asthma with persistent airflow limitation difficult, especially in smokers and elderly people.

Objective: The objective of the study was to study the clinical features, radiological and pulmonary function characteristics of patients having asthma-COPD overlap syndrome.

Materials and Methods: A cross-sectional study carried out at the Department of Respiratory Medicine, Government Medical College, Baroda, attached to SSG Hospital, Vadodara. A total of 100 patients enrolled which were clinically diagnosed with chronic airway obstruction as defined in the GOLD/GINA asthma-COPD overlap syndrome (ACOS) guidelines.

Results: In this study, a total of 100 patients were enrolled, out them 76 patients were male and 24 patients were female. Fifty-three patients were from urban area and 47 patients from rural area. Most patients belong to age ranging from 40 to 86. Ninety-nine patients had a breathlessness and it was the most common symptom followed by chronic cough in 93 patients, sputum production in 70 patients, wheezing in 70 patients, running nose in 65 patients, and chest tightness in 46 patients. In smoking history, 25 patients were current smoker, 49 patients were ex-smoker, and 26 patients had never smoked in their life. In pulmonary function test, 26 patients had a normal test, 13 patients had obstructive abnormality with no significant bronchodilator reversibility, 54 patients had a obstructive abnormality with significant bronchodilator reversibility, and 7 patients had a restrictive abnormality.

Conclusion: Clinically diagnosed ACOS patients were mostly males, belong to middle age groups, had breathlessness, wheezing, chronic cough with sputum production, and rhinitis and sneezing as the major symptoms. The pulmonary function tests revealed majority of the patients having obstructive pattern in pulmonary function test (spirometry). Furthermore, a majority of these patients had significant positive bronchodilatory response.

Key words: Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome; Pulmonary Function Test; Breathlessness


 
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Pubmed Style

Chauhan J, Patel B, Parekh C. Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome. Int J Med Sci Public Health. 2020; 9(6): 353-356. doi:10.5455/ijmsph.2020.06088202022062020


Web Style

Chauhan J, Patel B, Parekh C. Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome. http://www.ijmsph.com/?mno=115501 [Access: August 30, 2020]. doi:10.5455/ijmsph.2020.06088202022062020


AMA (American Medical Association) Style

Chauhan J, Patel B, Parekh C. Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome. Int J Med Sci Public Health. 2020; 9(6): 353-356. doi:10.5455/ijmsph.2020.06088202022062020



Vancouver/ICMJE Style

Chauhan J, Patel B, Parekh C. Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome. Int J Med Sci Public Health. (2020), [cited August 30, 2020]; 9(6): 353-356. doi:10.5455/ijmsph.2020.06088202022062020



Harvard Style

Chauhan, J., Patel, . B. & Parekh, . C. (2020) Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome. Int J Med Sci Public Health, 9 (6), 353-356. doi:10.5455/ijmsph.2020.06088202022062020



Turabian Style

Chauhan, Jayant, Bhavesh Patel, and Chirag Parekh. 2020. Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome. International Journal of Medical Science and Public Health, 9 (6), 353-356. doi:10.5455/ijmsph.2020.06088202022062020



Chicago Style

Chauhan, Jayant, Bhavesh Patel, and Chirag Parekh. "Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome." International Journal of Medical Science and Public Health 9 (2020), 353-356. doi:10.5455/ijmsph.2020.06088202022062020



MLA (The Modern Language Association) Style

Chauhan, Jayant, Bhavesh Patel, and Chirag Parekh. "Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome." International Journal of Medical Science and Public Health 9.6 (2020), 353-356. Print. doi:10.5455/ijmsph.2020.06088202022062020



APA (American Psychological Association) Style

Chauhan, J., Patel, . B. & Parekh, . C. (2020) Study of clinical, radiological, and pulmonary function characteristics of patients having asthma-chronic obstructive pulmonary disease overlap syndrome. International Journal of Medical Science and Public Health, 9 (6), 353-356. doi:10.5455/ijmsph.2020.06088202022062020





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