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Association between serum ferritin and thyroid hormone profile in hypothyroidism

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair.

Abstract
Background: Ferritin is an iron storage protein found in almost all of the body tissues. Serum ferritin levels also have been reported to be altered in patients with thyroid disease. Thus, changes in the serum concentrations of ferritin reflect thyroid function.

Objective: For the synthesis of thyroid hormones, thyroperoxidase requires iron. It has been suggested that there is an association between thyroid profile and ferritin levels, which is the storage protein for iron in the body. This study was undertaken to assess ferritin levels in hypothyroid patients.

Materials and Methods: Ferritin levels were estimated in 50 newly diagnosed patients of hypothyroidism using chemiluminescence technique (ADVIA Centaur CP). Total T3 and T4 levels were estimated using radioimmunoassay. Free T3, T4, and thyroid-stimulating hormone (TSH) levels were estimated using chemiluminescence. These were then compared with age- and sex-matched healthy controls. Results were correlated statistically.

Results: Serum ferritin levels were found to be significantly reduced in patients with hypothyroidism compared to normal subjects (p < 0.001).

Conclusion: Hypothyroidism is associated with low serum ferritin levels. The estimation of serum ferritin may help in understanding the etiopathogenesis, diagnosis, and monitoring of hypothyroid patients.

Key words: Ferritin, hypothyroidism, thyroid


 
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How to Cite this Article
Pubmed Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair. Association between serum ferritin and thyroid hormone profile in hypothyroidism. Int J Med Sci Public Health. 2015; 4(6): 863-865. doi:10.5455/ijmsph.2015.24012015174


Web Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair. Association between serum ferritin and thyroid hormone profile in hypothyroidism. http://www.ijmsph.com/?mno=178386 [Access: November 21, 2018]. doi:10.5455/ijmsph.2015.24012015174


AMA (American Medical Association) Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair. Association between serum ferritin and thyroid hormone profile in hypothyroidism. Int J Med Sci Public Health. 2015; 4(6): 863-865. doi:10.5455/ijmsph.2015.24012015174



Vancouver/ICMJE Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair. Association between serum ferritin and thyroid hormone profile in hypothyroidism. Int J Med Sci Public Health. (2015), [cited November 21, 2018]; 4(6): 863-865. doi:10.5455/ijmsph.2015.24012015174



Harvard Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair (2015) Association between serum ferritin and thyroid hormone profile in hypothyroidism. Int J Med Sci Public Health, 4 (6), 863-865. doi:10.5455/ijmsph.2015.24012015174



Turabian Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair. 2015. Association between serum ferritin and thyroid hormone profile in hypothyroidism. International Journal of Medical Science and Public Health, 4 (6), 863-865. doi:10.5455/ijmsph.2015.24012015174



Chicago Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair. "Association between serum ferritin and thyroid hormone profile in hypothyroidism." International Journal of Medical Science and Public Health 4 (2015), 863-865. doi:10.5455/ijmsph.2015.24012015174



MLA (The Modern Language Association) Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair. "Association between serum ferritin and thyroid hormone profile in hypothyroidism." International Journal of Medical Science and Public Health 4.6 (2015), 863-865. Print. doi:10.5455/ijmsph.2015.24012015174



APA (American Psychological Association) Style

Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair (2015) Association between serum ferritin and thyroid hormone profile in hypothyroidism. International Journal of Medical Science and Public Health, 4 (6), 863-865. doi:10.5455/ijmsph.2015.24012015174





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