E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi.

Abstract
Background: Improvement in glycemic control, particularly early in the treatment, is associated with reductions in the incidence of microvascular complications, including chronic kidney disease (CKD).

Objective: To study the effect of glycemic control on diabetic nephropathy (DN) in patients with type 2 diabetes.

Materials and Methods: We investigated progression of DN by measuring glycosylated hemoglobin (HbA1c), serum creatinine, and glomerular filtration rate (GFR) level in 70 (37 men and 33 women) patients with type 2 diabetes mellitus (DM) on antihypertensive treatment.

Result: The survey was done for 6 months during which 40 patients with DM (group 1) with serum creatinine <1.2 mg/dL were compared with 30 patients with DM (group 2) with serum creatinine ≥1.2 mg/dL who had mean HbA1c of 9.0%. In group 2, the mean level of serum creatinine (1.71 ± 0.46 mg/dL) was significantly higher and the mean GFR (54.57 ± 35.26 mL/min) was significantly lower than group 1 (P < 0.05).

Conclusion: Uncontrolled glycemic control leads to progression of DN with an earlier decline in GFR in patients with type 2 diabetes.

Key words: Glycemic control, GFR, serum creatinine, type 2 diabetes mellitus (DM)


 
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How to Cite this Article
Pubmed Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi. Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus. Int J Med Sci Public Health. 2016; 5(7): 1305-1308. doi:10.5455/ijmsph.2016.11072015192


Web Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi. Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus. http://www.ijmsph.com/?mno=196215 [Access: September 28, 2020]. doi:10.5455/ijmsph.2016.11072015192


AMA (American Medical Association) Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi. Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus. Int J Med Sci Public Health. 2016; 5(7): 1305-1308. doi:10.5455/ijmsph.2016.11072015192



Vancouver/ICMJE Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi. Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus. Int J Med Sci Public Health. (2016), [cited September 28, 2020]; 5(7): 1305-1308. doi:10.5455/ijmsph.2016.11072015192



Harvard Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi (2016) Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus. Int J Med Sci Public Health, 5 (7), 1305-1308. doi:10.5455/ijmsph.2016.11072015192



Turabian Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi. 2016. Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus. International Journal of Medical Science and Public Health, 5 (7), 1305-1308. doi:10.5455/ijmsph.2016.11072015192



Chicago Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi. "Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus." International Journal of Medical Science and Public Health 5 (2016), 1305-1308. doi:10.5455/ijmsph.2016.11072015192



MLA (The Modern Language Association) Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi. "Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus." International Journal of Medical Science and Public Health 5.7 (2016), 1305-1308. Print. doi:10.5455/ijmsph.2016.11072015192



APA (American Psychological Association) Style

Shital S Dodhia, Jigar D Barasara, Varsha S Joshi (2016) Glycemic control affects progression of kidney disease in patients with type 2 diabetes mellitus. International Journal of Medical Science and Public Health, 5 (7), 1305-1308. doi:10.5455/ijmsph.2016.11072015192





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