E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada.

Abstract
Background: Thalassemia is considered the most common genetic disorder worldwide. The condition affects economical and psychosocial quality of life of whole family broadly. It is a serious public health issue throughout Indian subcontinent and southeast Asia.

Objective: (1) To study the prevalence of transfusion transmitted infections (TTIs) in patients of beta-thalassemia major who are on transfusion therapy, (2) to assess the complications of iron overload and complications owing to chelation therapy, and (3) to study psychosocial and economic burden on patients’ family.

Materials and Methods: This cross-sectional study was conducted in Thalassemia ward of Pediatric Department from December 2010 to December 2011. All the patients of beta thalassemia major on blood transfusion therapy were included in the study. Preformed, pretested questionnaire was used to interview the patients and their caretakers. Data entry and analysis were done using Microsoft Excel 2007 and SPSS software, version 17.

Result: Prevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) was 3.95%, 2.25%, and 2.25%, respectively. Six in every 10 patients ever have experienced from blood transfusion reactions. Almost 40% patients had left the studies owing to illness or they have not gone to school ever.

Conclusion: Even after introduction of sensitive screening test, prevalence of TTIs is more in patients than general population. Quality of life is affected economically and psychosocially.

Key words: Transfusion transmitted infections (TTIs), consanguinity, iron overload, sickness absenteeism, splenectomy


 
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How to Cite this Article
Pubmed Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada. A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district. Int J Med Sci Public Health. 2016; 5(7): 1447-1451. doi:10.5455/ijmsph.2016.26082015230


Web Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada. A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district. http://www.ijmsph.com/?mno=200066 [Access: January 28, 2020]. doi:10.5455/ijmsph.2016.26082015230


AMA (American Medical Association) Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada. A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district. Int J Med Sci Public Health. 2016; 5(7): 1447-1451. doi:10.5455/ijmsph.2016.26082015230



Vancouver/ICMJE Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada. A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district. Int J Med Sci Public Health. (2016), [cited January 28, 2020]; 5(7): 1447-1451. doi:10.5455/ijmsph.2016.26082015230



Harvard Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada (2016) A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district. Int J Med Sci Public Health, 5 (7), 1447-1451. doi:10.5455/ijmsph.2016.26082015230



Turabian Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada. 2016. A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district. International Journal of Medical Science and Public Health, 5 (7), 1447-1451. doi:10.5455/ijmsph.2016.26082015230



Chicago Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada. "A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district." International Journal of Medical Science and Public Health 5 (2016), 1447-1451. doi:10.5455/ijmsph.2016.26082015230



MLA (The Modern Language Association) Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada. "A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district." International Journal of Medical Science and Public Health 5.7 (2016), 1447-1451. Print. doi:10.5455/ijmsph.2016.26082015230



APA (American Psychological Association) Style

Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yada (2016) A study on transfusion transmitted infections (TTIs), transfusion-related complications, and quality of life among the beta-thalassemia major patients in Jamnagar district. International Journal of Medical Science and Public Health, 5 (7), 1447-1451. doi:10.5455/ijmsph.2016.26082015230





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