E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T.

Cited by (1)

Abstract
Background: Even though red cell distribution width (RDW) and C reactive protein (CRP) are considered as markers of inflammation and cardiac injury studies on the diagnostic and/or prognostic applications of these parameters as renal markers in hypertension (HT) are scanty.

Objective: To evaluate the association, if any, between RDW and high sensitive CRP (hs-CRP) with renal complication in HT.

Materials and Methods: One hundred and twenty patients with clinically proved hypertension under treatment formed the test group and 60 age and sex matched healthy adults formed the control group. . Blood collected in EDTA was used for complete blood cell count (CBC). Serum was separated immediately after clotting and is used for the estimation of hs-CRP by particle enhanced immunonephelometry.

Results: A significant elevation in hs-CRP was observed in both the male and female patients with HT compared to the control group. In the case of RDW even though the values were higher in the test group than control, the elevation was significant only in the male test subjects indicating they are at a higher risk than the females.

Conclusion: The elevation of hs-CRP and RDW in the test group suggest that inflammation may be one of the cause or effect of hypertension. Long term inflammation may lead to chronic kidney disease and cardiovascular disease hence monitoring of these markers may be of use in predicting the outcome of hypertension.

Key words: Hypertension; Chronic Kidney Disease; End Stage Renal Disease; Red Cell Distribution Width; C - Reactive Protein


 
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This Article Cited By the following articles

The relationship between red blood cell distribution width and blood pressure abnormal dipping in patients with essential hypertension: a cross-sectional study
BMJ Open 2016; 6(2): e010456.

1
 
How to Cite this Article
Pubmed Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T. Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension. Int J Med Sci Public Health. 2012; 1(2): 138-142. doi:10.5455/ijmsph.2012.138-142


Web Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T. Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension. http://www.ijmsph.com/?mno=26886 [Access: January 20, 2019]. doi:10.5455/ijmsph.2012.138-142


AMA (American Medical Association) Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T. Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension. Int J Med Sci Public Health. 2012; 1(2): 138-142. doi:10.5455/ijmsph.2012.138-142



Vancouver/ICMJE Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T. Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension. Int J Med Sci Public Health. (2012), [cited January 20, 2019]; 1(2): 138-142. doi:10.5455/ijmsph.2012.138-142



Harvard Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T (2012) Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension. Int J Med Sci Public Health, 1 (2), 138-142. doi:10.5455/ijmsph.2012.138-142



Turabian Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T. 2012. Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension. International Journal of Medical Science and Public Health, 1 (2), 138-142. doi:10.5455/ijmsph.2012.138-142



Chicago Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T. "Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension." International Journal of Medical Science and Public Health 1 (2012), 138-142. doi:10.5455/ijmsph.2012.138-142



MLA (The Modern Language Association) Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T. "Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension." International Journal of Medical Science and Public Health 1.2 (2012), 138-142. Print. doi:10.5455/ijmsph.2012.138-142



APA (American Psychological Association) Style

Jithesh TK, Riju Mathew, Jayapal V, Vijayakumar T (2012) Red cell distribution width and high sensitivity C-reactive protein as risk markers in hypertension. International Journal of Medical Science and Public Health, 1 (2), 138-142. doi:10.5455/ijmsph.2012.138-142





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