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International Journal of Medical Science and Public Health

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Original Research Open Access


Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion

Gunjan P Upadhyay, Rameshchandra M Thakker.

Abstract
Background: Tuberculous pleural effusion is the second most common site of extrapulmonary tuberculosis. Not all centers have access to advanced and invasive tests and affordability is also an issue. Hence, diagnosis is largely based on history, clinical examination, and pleural fluid analysis.

Objectives: Our aim was to evaluate the utility of pleural fluid routine micro examination along with adenosine deaminase (ADA) levels in diagnosis of tuberculous pleural effusion.

Materials and Methods: A retrospective analysis was done of the 100 adult patients with pleural effusion predefined criteria were adopted to label a case as tuberculous. Using MS Excel 2007 sensitivity, specificity, positive and negative likelihood ratio, accuracy, etc., were derived and various parameters in pleural fluid were also studied.

Result: The sensitivity, specificity, positive, and negative predictive values, positive and negative likelihood ratios, accuracy, and discordance were 95.74%, 94.33%, 93.75%, 96.15%, 16.88%, 4.51%, 95%, and 5%, respectively.

Conclusion: Pleural fluid routine micro examination along with ADA levels has an acceptable sensitivity, specificity, and accuracy for the diagnosis of tuberculous pleural effusion.

Key words: Pleural Effusion; Adenosine Deaminase; Tuberculosis


 
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How to Cite this Article
Pubmed Style

Upadhyay GP, Thakker RM. Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion. Int J Med Sci Public Health. 2017; 6(11): 1562-1564. doi:10.5455/ijmsph.2017.0925511092017



Web Style

Upadhyay GP, Thakker RM. Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion. www.scopemed.org/?mno=277214 [Access: November 19, 2017]. doi:10.5455/ijmsph.2017.0925511092017



AMA (American Medical Association) Style

Upadhyay GP, Thakker RM. Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion. Int J Med Sci Public Health. 2017; 6(11): 1562-1564. doi:10.5455/ijmsph.2017.0925511092017



Vancouver/ICMJE Style

Upadhyay GP, Thakker RM. Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion. Int J Med Sci Public Health. (2017), [cited November 19, 2017]; 6(11): 1562-1564. doi:10.5455/ijmsph.2017.0925511092017



Harvard Style

Upadhyay, G. P. & Thakker, R. M. (2017) Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion. Int J Med Sci Public Health, 6 (11), 1562-1564. doi:10.5455/ijmsph.2017.0925511092017



Turabian Style

Upadhyay, Gunjan P, and Rameshchandra M Thakker. 2017. Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion. International Journal of Medical Science and Public Health , 6 (11), 1562-1564. doi:10.5455/ijmsph.2017.0925511092017



Chicago Style

Upadhyay, Gunjan P, and Rameshchandra M Thakker. "Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion." International Journal of Medical Science and Public Health 6 (2017), 1562-1564. doi:10.5455/ijmsph.2017.0925511092017



MLA (The Modern Language Association) Style

Upadhyay, Gunjan P, and Rameshchandra M Thakker. "Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion." International Journal of Medical Science and Public Health 6.11 (2017), 1562-1564. Print. doi:10.5455/ijmsph.2017.0925511092017



APA (American Psychological Association) Style

Upadhyay, G. P. & Thakker, R. M. (2017) Utility of pleural fluid routine and microscopy examination plus adenosine deaminase levels in the diagnosis of tuberculous pleural effusion. International Journal of Medical Science and Public Health , 6 (11), 1562-1564. doi:10.5455/ijmsph.2017.0925511092017



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