E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital

Nitesh Mohan, Amit Kumar, Parbodh Kumar.

Abstract
Background: Hepatitis B virus is a DNA virus, causing acute as well as chronic liver disease including cirrhosis & hepatocellular carcinoma. Carriers of Hepatitis B are asymptomatic individuals without manifest disease harboring infection and capable of transmitting infection. Transmission of infection occurs through blood transfusion, needles, body fluids and sexual intercourse. Clinical recognition of carrier state of HBV is more frequently done by detection of HBsAg in the serum. Hepatitis B infection is a serious global & public health problem. Worldwide over 2 billion people have been infected with HBV. India has been placed into the intermediate zone of prevalence of Hepatitis B. The infection is a leading cause of morbidity & mortality.

Aims & Objective: To study the Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital.

Material and Methods: The study was conducted at the Blood Bank of Rohilkhand Medical College and Hospital, Bareilly. In this retrospective study, healthy blood donors, over a period of three years were assessed. The blood donors were categorized as voluntary donors and replacement donors. Blood from donors were subjected to serological test for detection of HBsAg through ELISA based assay of Hepatitis B surface antigen.

Results: A total of 5088 blood donors were included in the study, 42 (0.82%) tested positive for hepatitis B surface antigen (HBsAg). Among these 42 cases, 41 (0.86%) were males and 01 (0.30%) was female.

Conclusion: The population based data on the prevalence of HBV presented here is likely to improve our understanding in disease transmission. A shift in donor age group pattern was observed, with higher prevalence of HBV in donors. This stresses upon the fact that extensive screening through routine and specialized tests is mandatory and definite criteria are to be given for donor selection so as to minimize the spread of this disease through transmission.

Key words: Hepatitis B Virus; Seroprevalence; HBsAg


 
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How to Cite this Article
Pubmed Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar. Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital. Int J Med Sci Public Health. 2013; 2(2): 204-207. doi:10.5455/ijmsph.2013.2.196-199


Web Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar. Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital. http://www.ijmsph.com/?mno=28061 [Access: August 29, 2020]. doi:10.5455/ijmsph.2013.2.196-199


AMA (American Medical Association) Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar. Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital. Int J Med Sci Public Health. 2013; 2(2): 204-207. doi:10.5455/ijmsph.2013.2.196-199



Vancouver/ICMJE Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar. Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital. Int J Med Sci Public Health. (2013), [cited August 29, 2020]; 2(2): 204-207. doi:10.5455/ijmsph.2013.2.196-199



Harvard Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar (2013) Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital. Int J Med Sci Public Health, 2 (2), 204-207. doi:10.5455/ijmsph.2013.2.196-199



Turabian Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar. 2013. Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital. International Journal of Medical Science and Public Health, 2 (2), 204-207. doi:10.5455/ijmsph.2013.2.196-199



Chicago Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar. "Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital." International Journal of Medical Science and Public Health 2 (2013), 204-207. doi:10.5455/ijmsph.2013.2.196-199



MLA (The Modern Language Association) Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar. "Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital." International Journal of Medical Science and Public Health 2.2 (2013), 204-207. Print. doi:10.5455/ijmsph.2013.2.196-199



APA (American Psychological Association) Style

Nitesh Mohan, Amit Kumar, Parbodh Kumar (2013) Seroprevalence of HBsAg among blood donors attending blood bank of a tertiary care hospital. International Journal of Medical Science and Public Health, 2 (2), 204-207. doi:10.5455/ijmsph.2013.2.196-199





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