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Case Report 


Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report

Ayse Arduc, Serhat Isik,, Berçem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler.

Abstract
Congenital and acquired thrombophilia are associated with an increased risk of pregnancy-associated venous thrombosis (VT). Several genetic mechanisms have been investigated for their possible relationship with VT. Methyl tetrahydrofolate reductase gene polymorphisms are frequently in the MTHFR gene, which leads to a C to T change at position 677, has been suggested to alter the thrombohemostasis process and thrombophilia (1). Also, it has been found that MTHFR C1298C or MTHFR A1298C have no effect on the risk of VT (1). Herein, we describe deep VT (DVT) secondary to heterozygous MTHFR A1298C mutation in pregnant woman.

Key words: Pregnancy; MTHFR A1298C mutation; Venous thrombosis


 
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PMid:20083915

How to Cite this Article
Pubmed Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler. Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report. Int J Med Sci Public Health. 2013; 2(1): 159-161. doi:10.5455/ijmsph.2013.2.159-161


Web Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler. Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report. http://www.ijmsph.com/?mno=28304 [Access: February 16, 2020]. doi:10.5455/ijmsph.2013.2.159-161


AMA (American Medical Association) Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler. Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report. Int J Med Sci Public Health. 2013; 2(1): 159-161. doi:10.5455/ijmsph.2013.2.159-161



Vancouver/ICMJE Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler. Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report. Int J Med Sci Public Health. (2013), [cited February 16, 2020]; 2(1): 159-161. doi:10.5455/ijmsph.2013.2.159-161



Harvard Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler (2013) Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report. Int J Med Sci Public Health, 2 (1), 159-161. doi:10.5455/ijmsph.2013.2.159-161



Turabian Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler. 2013. Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report. International Journal of Medical Science and Public Health, 2 (1), 159-161. doi:10.5455/ijmsph.2013.2.159-161



Chicago Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler. "Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report." International Journal of Medical Science and Public Health 2 (2013), 159-161. doi:10.5455/ijmsph.2013.2.159-161



MLA (The Modern Language Association) Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler. "Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report." International Journal of Medical Science and Public Health 2.1 (2013), 159-161. Print. doi:10.5455/ijmsph.2013.2.159-161



APA (American Psychological Association) Style

Ayse Arduc, Serhat Isik, , Bercem Aycicek Dogan, Ufuk Ozuguz, Gulhan Akbaba, Dilek Berker, Serdar Guler (2013) Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report. International Journal of Medical Science and Public Health, 2 (1), 159-161. doi:10.5455/ijmsph.2013.2.159-161





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