E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date.

Abstract
Background: The benefits of optimum blood pressure (BP) control in patients with diabetes exceed the benefits of glycaemic control and extend to the prevention of both macro-vascular and micro-vascular complications in patients suffering from both hypertension and diabetes mellitus.

Aims & Objective: To investigate the utilization patterns of anti-hypertensive drugs and to evaluate blood pressure (BP) control among diabetic-hypertensive patients with and without reduced renal function.

Material and Methods: A prospective, observational study carried out at medicine department of SBKS Medical College and Research Centre, Piparia. The pattern of use of antihypertensive drugs in 50 hypertensive-diabetic patients was evaluated in correlation with its renal function and BP control achieved was compared in patients with and without reduced renal function.

Results: Total 63 antihypertensive medication episodes were prescribed for 50 patients. Out of which 76% patients were receiving 1 drug, 22% receiving 2 drugs and 2% receiving 3 drugs of different antihypertensive class. Most patients were receiving Angiotensin-Converting-Enzyme-Inhibitors (ACE-I)/Angiotensin-Receptor-Blockers (ARBs) (60%), followed by CCBs (24%), beta-blockers (20%), and diuretics (16%). Patients on monotherapy were mostly receiving ACE-I/ARB (65.78%). Beta blockers were more commonly prescribed in patients with reduced renal function (p=0.005). BP control was achieved in 63.15% patients in monotherapy and 33.33% in polytherapy group. Control of systolic and diastolic BP was significantly higher in patients without reduced renal function than patients with reduced renal function (p<0.05).

Conclusion: There was suboptimum use of combination therapy among diabetic-hypertensive patients in general and specifically in developing countries as reflected by control achieved in systolic and diastolic BP which requires concern of all healthcare professionals.

Key words: Blood pressure control, Hypertensive – Diabetic patients, Prescribing patterns, Antihypertensive drugs, Renal function, Evidence based medicine


 
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How to Cite this Article
Pubmed Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date. Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital. Int J Med Sci Public Health. 2013; 2(2): 175-180. doi:10.5455/ijmsph.2013.2.167-172


Web Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date. Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital. http://www.ijmsph.com/?mno=29243 [Access: February 16, 2020]. doi:10.5455/ijmsph.2013.2.167-172


AMA (American Medical Association) Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date. Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital. Int J Med Sci Public Health. 2013; 2(2): 175-180. doi:10.5455/ijmsph.2013.2.167-172



Vancouver/ICMJE Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date. Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital. Int J Med Sci Public Health. (2013), [cited February 16, 2020]; 2(2): 175-180. doi:10.5455/ijmsph.2013.2.167-172



Harvard Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date (2013) Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital. Int J Med Sci Public Health, 2 (2), 175-180. doi:10.5455/ijmsph.2013.2.167-172



Turabian Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date. 2013. Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital. International Journal of Medical Science and Public Health, 2 (2), 175-180. doi:10.5455/ijmsph.2013.2.167-172



Chicago Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date. "Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital." International Journal of Medical Science and Public Health 2 (2013), 175-180. doi:10.5455/ijmsph.2013.2.167-172



MLA (The Modern Language Association) Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date. "Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital." International Journal of Medical Science and Public Health 2.2 (2013), 175-180. Print. doi:10.5455/ijmsph.2013.2.167-172



APA (American Psychological Association) Style

Jay Shah, Tejas Khakhkhar, Saurabh Bhirud, Rima B Shah, Sanjay Date (2013) Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital. International Journal of Medical Science and Public Health, 2 (2), 175-180. doi:10.5455/ijmsph.2013.2.167-172





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