E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Clinical profile of cases of alcoholic liver disease

Hemang Suthar, Kaushal Suthar, Bhavna Mewada.

Cited by (4)

Abstract
Background: Alcohol is most common substance abused. Alcoholic liver disease is a major health care problem in India. Alcohol consumption is directly associated with liver disease mortality and accounts for increased social and economic costs. Alcoholic liver disease may take the forms of acute involvement (alcoholic hepatitis) or chronic liver disease (steatosis, steatohepatitis, fibrosis and cirrhosis. The severity and prognosis of alcohol- induced liver disease depends on the amount, pattern and duration of alcohol consumption, as well as on the presence of liver inflammation, diet, nutritional status and genetic predisposition of an individual. While steatosis is complete benign disease, liver cirrhosis is associated with marked morbidity, mortality and life expectancy shortening.

Aims & Objective: To study alcoholic liver disease, clinical presentation, to access the severity of alcoholic liver disease and its complications and their treatment response and overall outcome among patients using laboratory and radiological parameters.

Material and Methods: A total of 50 patients were studied and their clinical profile, laboratory parameters and radiological investigations were taken.

Results: Among 50 patients 58 % belonged to age group 40-49 years. All were male. 78 % of patients from urban areas, with 60 % belonging to middle class.60 % of patients have chief complaint of abdominal distension and melena each. Jaundice (60%) and ascites (60%) were commonest finding. All patients had raised SGPT, SGOT, S.AlPO4 and S. bilirubin suggesting liver damage. Prolonged PT and reduced S. albumin suggested reduced protein synthesis because of liver disease. Alcoholic hepatitis was in24% cases, while 40% had fatty liver and 36 % had alcoholic cirrhosis. Overall mortality rate was 20 %. , most common cause is encephalopathy (40%), coagulopathy leading to DIC (40%) and hepatorenal syndrome (20%).

Conclusion: Alcoholic liver disease was seen among the productive age group with high morbidity and mortality. Mortality and morbidity associated with this disease is matter of serious economic loss to the nation and grief for the society

Key words: Alcohol; Alcoholic Liver Disease; Clinical Profile


 
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This Article Cited By the following articles

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How to Cite this Article
Pubmed Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada. Clinical profile of cases of alcoholic liver disease. Int J Med Sci Public Health. 2013; 2(2): 394-398. doi:10.5455/ijmsph.2013.2.408-412


Web Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada. Clinical profile of cases of alcoholic liver disease. http://www.ijmsph.com/?mno=31625 [Access: February 15, 2020]. doi:10.5455/ijmsph.2013.2.408-412


AMA (American Medical Association) Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada. Clinical profile of cases of alcoholic liver disease. Int J Med Sci Public Health. 2013; 2(2): 394-398. doi:10.5455/ijmsph.2013.2.408-412



Vancouver/ICMJE Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada. Clinical profile of cases of alcoholic liver disease. Int J Med Sci Public Health. (2013), [cited February 15, 2020]; 2(2): 394-398. doi:10.5455/ijmsph.2013.2.408-412



Harvard Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada (2013) Clinical profile of cases of alcoholic liver disease. Int J Med Sci Public Health, 2 (2), 394-398. doi:10.5455/ijmsph.2013.2.408-412



Turabian Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada. 2013. Clinical profile of cases of alcoholic liver disease. International Journal of Medical Science and Public Health, 2 (2), 394-398. doi:10.5455/ijmsph.2013.2.408-412



Chicago Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada. "Clinical profile of cases of alcoholic liver disease." International Journal of Medical Science and Public Health 2 (2013), 394-398. doi:10.5455/ijmsph.2013.2.408-412



MLA (The Modern Language Association) Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada. "Clinical profile of cases of alcoholic liver disease." International Journal of Medical Science and Public Health 2.2 (2013), 394-398. Print. doi:10.5455/ijmsph.2013.2.408-412



APA (American Psychological Association) Style

Hemang Suthar, Kaushal Suthar, Bhavna Mewada (2013) Clinical profile of cases of alcoholic liver disease. International Journal of Medical Science and Public Health, 2 (2), 394-398. doi:10.5455/ijmsph.2013.2.408-412





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