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Factors influencing yield of platelet aphaeresis using continuous flow cell separator

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani.

Cited by (1)

Abstract
Background: In Transfusion Medicine, screening for suitable donor for platelet aphaeresis is difficult and time consuming procedure. This might lead to delayed supply of life saving Single Donor Platelet to critically bleeding patient.

Aims & Objective: The aim of this study was to analyse the effect of various donor and procedure related parameters on the yield of single donor platelet so that the transfusionist as well as clinician can screen blood donors effectively in less time. Pre-donation platelet count, haemoglobin, haematocrit & weight were included as donor related variables. Processing time and blood volume processed were assessed as procedure related variables.

Material and Methods: A total number of 265 platelet aphaeresis procedures were performed on CS 3000 plus with AMS cell separator (Fenwal, USA) using closed & open system aphaeresis kits & studied with respect to donor’s, procedure’s & patient’s related data. The statistical analysis used in this study was Pearson Correlation (‘r’ value).

Results: The mean pre-donation platelet count was 286 ± 55 x 103/cu mm & mean platelet yield of all procedures was 3.3 ± 0.68 x 1011.

Conclusion: Platelet yield correlated positively with pre-donation platelet count (r = 0.302, P < 0.0001). Donor’s weight, haemoglobin & haematocrit were not correlated with the yield & did not affect the yield of single donor platelets.

Key words: Cell Separator; Haemoglobin; Platelet Count; Plateletpheresis; Single Donor Platelet; Weight


 
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This Article Cited By the following articles

A Study on Influence of Donor Hematocrit on the Procedural Parameters of Concentrated Single Donor Platelets Collected by Two Apheresis Devices
Indian J Hematol Blood Transfus 2019; (): .

1
 
How to Cite this Article
Pubmed Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani. Factors influencing yield of platelet aphaeresis using continuous flow cell separator. Int J Med Sci Public Health. 2013; 2(2): 309-312. doi:10.5455/ijmsph.2013.2.323-326


Web Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani. Factors influencing yield of platelet aphaeresis using continuous flow cell separator. http://www.ijmsph.com/?mno=31903 [Access: February 16, 2020]. doi:10.5455/ijmsph.2013.2.323-326


AMA (American Medical Association) Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani. Factors influencing yield of platelet aphaeresis using continuous flow cell separator. Int J Med Sci Public Health. 2013; 2(2): 309-312. doi:10.5455/ijmsph.2013.2.323-326



Vancouver/ICMJE Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani. Factors influencing yield of platelet aphaeresis using continuous flow cell separator. Int J Med Sci Public Health. (2013), [cited February 16, 2020]; 2(2): 309-312. doi:10.5455/ijmsph.2013.2.323-326



Harvard Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani (2013) Factors influencing yield of platelet aphaeresis using continuous flow cell separator. Int J Med Sci Public Health, 2 (2), 309-312. doi:10.5455/ijmsph.2013.2.323-326



Turabian Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani. 2013. Factors influencing yield of platelet aphaeresis using continuous flow cell separator. International Journal of Medical Science and Public Health, 2 (2), 309-312. doi:10.5455/ijmsph.2013.2.323-326



Chicago Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani. "Factors influencing yield of platelet aphaeresis using continuous flow cell separator." International Journal of Medical Science and Public Health 2 (2013), 309-312. doi:10.5455/ijmsph.2013.2.323-326



MLA (The Modern Language Association) Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani. "Factors influencing yield of platelet aphaeresis using continuous flow cell separator." International Journal of Medical Science and Public Health 2.2 (2013), 309-312. Print. doi:10.5455/ijmsph.2013.2.323-326



APA (American Psychological Association) Style

Jitendra Patel, Arpita Nishal, Amrish Pandya, Prashant J Patel, Sangita Wadhwani (2013) Factors influencing yield of platelet aphaeresis using continuous flow cell separator. International Journal of Medical Science and Public Health, 2 (2), 309-312. doi:10.5455/ijmsph.2013.2.323-326





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