E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers

Lekha Tejaswi Y, Preethi B P, Kshiti Mouli Kondajji.

Abstract
Background: Hypertensive disorders of pregnancy are a multifactorial disease with oxidative stress also contributing to the etiopathogenesis. Assessment of maternal and neonatal oxidative stress may provide insight into early identification of at-risk mothers and neonates and timely intervention to reduce morbidity and mortality associated with hypertensive disorders.

Objective: The objective of the study was to evaluate whether there occurs a reflection of oxidative stress in neonates born to hypertensive mothers.

Materials and Methods: A total of 100 pregnant women of which 50 were normotensive and 50 were pre-eclamptic were tested for serum uric acid and serum malondialdehyde (MDA) in maternal blood and cord blood of their newborns. Our observations were subjected to statistical analysis Mean ± standard deviation calculated. Comparison is done by student t-test. Relationship between parameters was evaluated by Pearson’s correlation.

Results: Increased levels of serum uric acid and MDA were found in maternal and cord blood in hypertensive pregnancies, indicative of oxidative stress. However, cord blood MDA and uric acid levels were lower than the corresponding maternal blood levels.

Conclusion: Our study findings suggest that oxidative stress in hypertensive mothers is reflected in their neonates.

Key words: Pre-eclampsia; Serum Uric Acid; Serum Malondialdehyde; Oxidative Stress; Maternal and Cord Blood


 
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How to Cite this Article
Pubmed Style

Y LT, P PB, Kondajji KM. Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers. Int J Med Sci Public Health. 2019; 8(7): 534-538. doi:10.5455/ijmsph.2019.0307116052019


Web Style

Y LT, P PB, Kondajji KM. Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers. http://www.ijmsph.com/?mno=37241 [Access: November 12, 2019]. doi:10.5455/ijmsph.2019.0307116052019


AMA (American Medical Association) Style

Y LT, P PB, Kondajji KM. Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers. Int J Med Sci Public Health. 2019; 8(7): 534-538. doi:10.5455/ijmsph.2019.0307116052019



Vancouver/ICMJE Style

Y LT, P PB, Kondajji KM. Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers. Int J Med Sci Public Health. (2019), [cited November 12, 2019]; 8(7): 534-538. doi:10.5455/ijmsph.2019.0307116052019



Harvard Style

Y, L. T., P, . P. B. & Kondajji, . K. M. (2019) Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers. Int J Med Sci Public Health, 8 (7), 534-538. doi:10.5455/ijmsph.2019.0307116052019



Turabian Style

Y, Lekha Tejaswi, Preethi B P, and Kshiti Mouli Kondajji. 2019. Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers. International Journal of Medical Science and Public Health, 8 (7), 534-538. doi:10.5455/ijmsph.2019.0307116052019



Chicago Style

Y, Lekha Tejaswi, Preethi B P, and Kshiti Mouli Kondajji. "Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers." International Journal of Medical Science and Public Health 8 (2019), 534-538. doi:10.5455/ijmsph.2019.0307116052019



MLA (The Modern Language Association) Style

Y, Lekha Tejaswi, Preethi B P, and Kshiti Mouli Kondajji. "Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers." International Journal of Medical Science and Public Health 8.7 (2019), 534-538. Print. doi:10.5455/ijmsph.2019.0307116052019



APA (American Psychological Association) Style

Y, L. T., P, . P. B. & Kondajji, . K. M. (2019) Evaluation of reflection of oxidative stress in cord blood of neonates born to hypertensive mothers. International Journal of Medical Science and Public Health, 8 (7), 534-538. doi:10.5455/ijmsph.2019.0307116052019





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