E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Early diagnosis and evaluation of neonatal septicemia by hematological scoring system

Hiral P Shah, Bharti M Jha.

Abstract
Background: Neonatal septicemia is a major health problem. Morbidity and mortality in the neonatal period are mostly due to neonatal septicemia.

Objective: The present study was undertaken to highlight the importance of hematological scoring system (HSS) in the early diagnosis and evaluation of neonatal septicemia and to correlate these hematological parameters with blood culture and C-reactive protein.

Materials and Methods: This study was prospective and was done over the period of 1 year including 100 clinically suspected neonatal septicemia cases admitted in neonatal intensive care unit. Hematological parameters were measured in all cases. Culture positivity was taken as the criterion for definitive diagnosis. Specificity, sensitivity, positive predictive value, negative predictive value, and P value were calculated for each hematological parameter.

Results: Of 100 clinically suspected neonates with sepsis studied, 19% were culture positive, 63.2% were male, 84.2% were term neonates, and 84.2% were low birth weight neonates (<2.5 kg). Early onset septicemia was more common (73.6%). In neonates who were delivered by spontaneous vaginal delivery (73.7%), septicemia was more common and also in neonates who were delivered in the hospital (84.2%). Klebsiella pneumoniae was the most common organism isolated (36.8%). By comparison of Rodwell’s HSS with blood culture results, it was found that the presence of likelihood of sepsis with score ≥3 was 59.25 % and with score ≥5 was 100%. With score ≤2, the likelihood of sepsis was absent (95.9%).

Conclusion: HSS is useful for distinguishing the infected infants from non-infected infants. It is also useful to provide an effective guideline for making decisions regarding the proper use of antibiotics for early treatment.

Key words: Hematological scoring system; Neonatal septicemia; Early diagnosis; Evaluation


 
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How to Cite this Article
Pubmed Style

Shah HP, Jha BM. Early diagnosis and evaluation of neonatal septicemia by hematological scoring system. Int J Med Sci Public Health. 2019; 8(6): 409-414. doi:10.5455/ijmsph.2019.0306330032019


Web Style

Shah HP, Jha BM. Early diagnosis and evaluation of neonatal septicemia by hematological scoring system. http://www.ijmsph.com/?mno=38270 [Access: August 20, 2019]. doi:10.5455/ijmsph.2019.0306330032019


AMA (American Medical Association) Style

Shah HP, Jha BM. Early diagnosis and evaluation of neonatal septicemia by hematological scoring system. Int J Med Sci Public Health. 2019; 8(6): 409-414. doi:10.5455/ijmsph.2019.0306330032019



Vancouver/ICMJE Style

Shah HP, Jha BM. Early diagnosis and evaluation of neonatal septicemia by hematological scoring system. Int J Med Sci Public Health. (2019), [cited August 20, 2019]; 8(6): 409-414. doi:10.5455/ijmsph.2019.0306330032019



Harvard Style

Shah, H. P. & Jha, . B. M. (2019) Early diagnosis and evaluation of neonatal septicemia by hematological scoring system. Int J Med Sci Public Health, 8 (6), 409-414. doi:10.5455/ijmsph.2019.0306330032019



Turabian Style

Shah, Hiral P, and Bharti M Jha. 2019. Early diagnosis and evaluation of neonatal septicemia by hematological scoring system. International Journal of Medical Science and Public Health, 8 (6), 409-414. doi:10.5455/ijmsph.2019.0306330032019



Chicago Style

Shah, Hiral P, and Bharti M Jha. "Early diagnosis and evaluation of neonatal septicemia by hematological scoring system." International Journal of Medical Science and Public Health 8 (2019), 409-414. doi:10.5455/ijmsph.2019.0306330032019



MLA (The Modern Language Association) Style

Shah, Hiral P, and Bharti M Jha. "Early diagnosis and evaluation of neonatal septicemia by hematological scoring system." International Journal of Medical Science and Public Health 8.6 (2019), 409-414. Print. doi:10.5455/ijmsph.2019.0306330032019



APA (American Psychological Association) Style

Shah, H. P. & Jha, . B. M. (2019) Early diagnosis and evaluation of neonatal septicemia by hematological scoring system. International Journal of Medical Science and Public Health, 8 (6), 409-414. doi:10.5455/ijmsph.2019.0306330032019





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