E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi.

Abstract
Background: Cancers of the upper aero-digestive tract (UADT) constitute 3.5-4% of all malignancies. Majority of cases
are squamous cell carcinomas which are related with various epidemiologic factors.

Aims & Objective: The objective of this study is to know the histopathological spectrum of tumours of UADT.

Material and Methods: This study comprises of 156 cases of histopathological diagnosed tumours of upper aero
digestive tract who attended new civil hospital, government medical college, Surat, from August 2010 to august 2012.
All prospective and neoplastic cases were included and retrospective and non- neoplastic cases were excluded. Routine
paraffin sectioning and staining was done and immunohistochemistry was applied when required.

Results: Out of total 156 cases of UADT, 129 malignant, 19 cases benign and 8 were carcinoma in-situ cases. In
malignant cases, 124 (96.00%) cases of carcinomas, 1 (0.80%) case of sarcoma, 2 (1.60%) cases of melanoma, and 2
(1.60%) cases were of lymphomas. Most common site of carcinoma was oral cavity (tongue). Most common carcinoma
was Squamous cell carcinoma. Most common site of SCC was hypo pharynx (pyriform Fossa), followed by oral cavity
(tongue) and larynx (supra glottis). In benign tumours, most common site was nasal cavity (7 cases) and common
varieties were Angiofibroma and Capillary Haemangioma.

Conclusion: Tumours of UADT are predominant in males affecting older age group. People with tobacco chewing,
smoking, alcoholism, poor socioeconomic background, mixed diet and poor oral hygiene are more vulnerable.

Key words: Upper aero digestive tract tumours, Squamous cell carcinoma, Oral cavity.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Vasudha Mahendra Bhagat
Articles by Peeyush kumar Saini
Articles by Hemali Jayantilal Tailor
Articles by Reena Balvant bhai Dudhat
Articles by Amita Ramesh bhai Patel
Articles by Jigna Pravin chandra Modi
on Google
on Google Scholar
Article Statistics
 Viewed: 1949
Downloaded: 560
Cited: 0

REFERENCES
1. Muir C, Weiland L. Upper aerodigestive tract cancers. Cancer 1995;75(1 Suppl):147-53.
2. Cho KJ, Khang SK, Lee SS, Koh JS, Chung JH, Lee YS, et al. Cancers of the Upper Aero digestive Tract in Korea. J Korean Med Sci. 2002;17(1):18-22.
3. Hammer JE. Aetiology and epidemiology of oral cancer. In: Carl W, Sakok K, (eds). Cancer and the oral cavity. Chicago: Quintessence Publishing Co. 1986.
4. Zygogianni AG, Kyrgias G, Karakitsos P, Psyrri A, Kouvaris J, Kelekis N, et al. Oral squamous cell cancer: early detection and the role of alcohol and smoking. Head Neck Oncol. 2011;3:2. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
5. Skarsgard DP, Groome PA, Mackillop WJ, Zhou S, Rothwell D, Dixon PF, et al. Cancers of the upper aero digestive tract in Ontario, Canada, and the United States. Cancer. 2000;88(7):1728-38. [DOI via Crossref]   
6. Sajid M, Singh JB, Ali S, Chanda N, Ahmed S, Ahmed M. Cancers of upper aerodigestive tract in Kashmir a clinicopathologic study. JK Practioners. 2004;11(1):17-20.
7. Franceschi S, Talamini R, Barra S, Barón AE, Negri E, Bidoli E, et al. Smoking and drinking in relation to the cancers of oral cavity, pharynx, larynx and esophagus in northern Italy. Cancer Res. 1990;50(20):6502-7.
8. Thakur BS. Oral and oropharyngeal tumours, clinicopathological study of 243 tumours (1991-1997), Karnataka. Karnataka University. 1998.
9. Sharma RN. Oral carcinoma –A clinical study of 122 cases. J Indian Med Assoc. 1964;43:263-8.
10. 10 Mehrotra R, Pandya S, Chaudhary AK, Kumar M, Singh M. Prevalence of oral premalignant and malignant lesions at a tertiary level hospital in Allahabad, India, Asian Pac J Cancer Prev. 2008;9(2):263-5.
11. Dias GS, Almeida AP. A histological and clinical study on oral cancers, descriptive analysis of 365 cases. Med Oral Patol Oral Cir Bucal. 2007;12(7):E474-8.
12. Khandekar SP, Bagday PS, Tiwari RR. Oral cancers and some epidemiological factors. A hospital based study. Indian J Community Med. 2006;31(3):157-9.
13. Balaram P, Sridhar H, Rajkumar T, Vaccarella S, Herrero R, Nandakumar A, et al. Oral cancers in southern India: The influence of smoking , drinking, tobacco chewing, and oral hygiene, Int J Cancer. 2002;98(3):440-5.
14. Notani PN, Jayant K. Role of diet in tumours of upper aerodigestive tract cancers. Nutr Cancer. 1987;10(1-2): 103-13.
15. Chainani-Wu N. Diet and oral, pharyngeal and esopharyngeal cancer. Nutr Cancer. 2002; 44(2):104-26. [DOI via Crossref]    [Pubmed]   
16. Behnaud F, Torabian, Zargaram M. Relationship between oral poor hygiene and broken teeth with oral tongue squamous cell carcinoma. Acta Medica Iran. 2011;49(3):159-62.
17. Kingdom TT, Kaplan MJ. Mucosal melanoma of the nasal cavity and paranasal sinuses. Head Neck. 1995;17(3):184-9. [DOI via Crossref]   
18. De Matos P, Tyler DS, Seigler HF. Malignant melanoma of the mucous membranes: a review of 119 cases. Ann Surg Oncol. 1998;5(8):733-42. [DOI via Crossref]   

How to Cite this Article
Pubmed Style

Bhagat VM, Saini Pk, Tailor HJ, Dudhat RBb, Patel ARb, Modi JPc. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. Int J Med Sci Public Health. 2013; 2(4): 971-974. doi:10.5455/ijmsph.2013.090720133


Web Style

Bhagat VM, Saini Pk, Tailor HJ, Dudhat RBb, Patel ARb, Modi JPc. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. http://www.ijmsph.com/?mno=40359 [Access: July 18, 2018]. doi:10.5455/ijmsph.2013.090720133


AMA (American Medical Association) Style

Bhagat VM, Saini Pk, Tailor HJ, Dudhat RBb, Patel ARb, Modi JPc. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. Int J Med Sci Public Health. 2013; 2(4): 971-974. doi:10.5455/ijmsph.2013.090720133



Vancouver/ICMJE Style

Bhagat VM, Saini Pk, Tailor HJ, Dudhat RBb, Patel ARb, Modi JPc. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. Int J Med Sci Public Health. (2013), [cited July 18, 2018]; 2(4): 971-974. doi:10.5455/ijmsph.2013.090720133



Harvard Style

Bhagat, V. M., Saini, P. k., Tailor, H. J., Dudhat, R. B. b., Patel, A. R. b. & Modi, J. P. c. (2013) Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. Int J Med Sci Public Health, 2 (4), 971-974. doi:10.5455/ijmsph.2013.090720133



Turabian Style

Bhagat, Vasudha Mahendra, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, and Jigna Pravin chandra Modi. 2013. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. International Journal of Medical Science and Public Health, 2 (4), 971-974. doi:10.5455/ijmsph.2013.090720133



Chicago Style

Bhagat, Vasudha Mahendra, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, and Jigna Pravin chandra Modi. "Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases." International Journal of Medical Science and Public Health 2 (2013), 971-974. doi:10.5455/ijmsph.2013.090720133



MLA (The Modern Language Association) Style

Bhagat, Vasudha Mahendra, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, and Jigna Pravin chandra Modi. "Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases." International Journal of Medical Science and Public Health 2.4 (2013), 971-974. Print. doi:10.5455/ijmsph.2013.090720133



APA (American Psychological Association) Style

Bhagat, V. M., Saini, P. k., Tailor, H. J., Dudhat, R. B. b., Patel, A. R. b. & Modi, J. P. c. (2013) Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. International Journal of Medical Science and Public Health, 2 (4), 971-974. doi:10.5455/ijmsph.2013.090720133





Most Viewed Articles
  • Management of Appendicular Lump: Early exploration Vs conservative management
    Chandra Prakash Pandey, Ram Chandra Kesharwani, Chandra Gopal Singh Chauhan, Manmohan Krishna Pandey, Purnima Mittra, Pramod Kumar, Arshad Raza
    Int J Med Sci Public Health. 2013; 2(4): 1046-1049
    » Abstract & References » doi: 10.5455/ijmsph.2013.230820131

  • Burden of non communicable diseases in India: Setting priority for action
    Kalpa Sharma
    Int J Med Sci Public Health. 2013; 2(1): 7-11
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.7-11

  • Internet addiction among professional courses students: A study from central India
    Arvind Sharma, Rupesh Sahu, Pradeep Kumar Kasar, Richa Sharma
    Int J Med Sci Public Health. 2014; 3(9): 1069-1073
    » Abstract & References » doi: 10.5455/ijmsph.2014.180620142

  • Diabetic nephropathy: Progression and pathophysiology
    Deepak N Parchwani, Amit A Upadhyah
    Int J Med Sci Public Health. 2012; 1(2): 59-70
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.59-70

  • Elevated levels of serum uric acid, creatinine or urea in preeclamptic women
    Magna Manjareeka, Sitikantha Nanda
    Int J Med Sci Public Health. 2013; 2(1): 43-47
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.43-47

  • Maternal and fetal outcome in oligohydramnios- Study of 100 cases
    Krishna Jagatia, Nisha Singh, Sachin Patel
    Int J Med Sci Public Health. 2013; 2(3): 724-727
    » Abstract & References » doi: 10.5455/ijmsph.2013.070520132

  • Zinc: The trace element of major importance in human nutrition and health
    Jayant D Deshpande, Mohini M Joshi, Purushottam A Giri
    Int J Med Sci Public Health. 2013; 2(1): 1-6
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.1-6

  • Knowledge, Attitude, and Practices (KAP) study on HIV / AIDS among HIV patients, care givers and general population in north-eastern part of India.
    L P Meena, S K Pandey, M Rai, Anju Bharti, Shyam Sunder
    Int J Med Sci Public Health. 2013; 2(1): 36-42
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.36-42

  • Patient satisfaction about health care services: A cross sectional study of patients who visit the outpatient department of a civil hospital at Surendranagar, Gujarat
    Krupal Joshi, Kishor Sochaliya, Shyamal Purani, Girija Kartha
    Int J Med Sci Public Health. 2013; 2(3): 659-663
    » Abstract & References » doi: 10.5455/ijmsph.2013.250420131

  • Prevalence and pattern of substance abuse among school childern in nothern India: A rapid assesment study
    Syed Shuja Qadri, RKD Goel, Jagjeet Singh, Surendra Kumar Ahluwalia, Rambha Pathak, Humaira Bashir
    Int J Med Sci Public Health. 2013; 2(2): 273-282
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.271-280

  • Most Downloaded
  • Internet addiction among professional courses students: A study from central India
    Arvind Sharma, Rupesh Sahu, Pradeep Kumar Kasar, Richa Sharma
    Int J Med Sci Public Health. 2014; 3(9): 1069-1073
    » Abstract & References » doi: 10.5455/ijmsph.2014.180620142

  • Diabetic nephropathy: Progression and pathophysiology
    Deepak N Parchwani, Amit A Upadhyah
    Int J Med Sci Public Health. 2012; 1(2): 59-70
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.59-70

  • Burden of non communicable diseases in India: Setting priority for action
    Kalpa Sharma
    Int J Med Sci Public Health. 2013; 2(1): 7-11
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.7-11

  • Gunthers with haemolytic anaemia extremly rare: A case report
    Nilesh Kumar, Ankur Varshney, Arvind Anand, Dibyaranjan Behera, Ravi Anand, Ashutosh Tiwari
    Int J Med Sci Public Health. 2013; 2(2): 472-474
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.313-315

  • Zinc: The trace element of major importance in human nutrition and health
    Jayant D Deshpande, Mohini M Joshi, Purushottam A Giri
    Int J Med Sci Public Health. 2013; 2(1): 1-6
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.1-6

  • Knowledge, Attitude, and Practices (KAP) study on HIV / AIDS among HIV patients, care givers and general population in north-eastern part of India.
    L P Meena, S K Pandey, M Rai, Anju Bharti, Shyam Sunder
    Int J Med Sci Public Health. 2013; 2(1): 36-42
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.36-42

  • Recent update on osteoporosis
    Vijender Agrawal, Dharmendra Gupta
    Int J Med Sci Public Health. 2013; 2(2): 164-168
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.162-166

  • Maternal and fetal outcome in oligohydramnios- Study of 100 cases
    Krishna Jagatia, Nisha Singh, Sachin Patel
    Int J Med Sci Public Health. 2013; 2(3): 724-727
    » Abstract & References » doi: 10.5455/ijmsph.2013.070520132

  • Study of psychological stress among undergraduate medical students of government medical college, Surat.
    Priti Solanky, Binita Desai, Abhay Kavishwar, S. L. Kantharia
    Int J Med Sci Public Health. 2012; 1(2): 38-42
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.38-42

  • Patient satisfaction about health care services: A cross sectional study of patients who visit the outpatient department of a civil hospital at Surendranagar, Gujarat
    Krupal Joshi, Kishor Sochaliya, Shyamal Purani, Girija Kartha
    Int J Med Sci Public Health. 2013; 2(3): 659-663
    » Abstract & References » doi: 10.5455/ijmsph.2013.250420131

  • Most Cited Articles
  • Zinc: The trace element of major importance in human nutrition and health
    Jayant D Deshpande, Mohini M Joshi, Purushottam A Giri
    Int J Med Sci Public Health. 2013; 2(1): 1-6
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.1-6
    Cited : 21 times [Click to see citing articles]

  • Burden of non communicable diseases in India: Setting priority for action
    Kalpa Sharma
    Int J Med Sci Public Health. 2013; 2(1): 7-11
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.7-11
    Cited : 13 times [Click to see citing articles]

  • Non albicans Candida species: its isolation pattern, species distribution, virulence factors and antifungal susceptibility profile
    Sachin Chandrakant Deorukhkar, Santosh Saini
    Int J Med Sci Public Health. 2013; 2(3): 533-538
    » Abstract & References » doi: 10.5455/ijmsph.2013.080320131
    Cited : 6 times [Click to see citing articles]

  • Clinico-microbiological profile of women with vaginal discharge in a tertiary care hospital of northern India
    Varsha Chaudhary, Ved Prakesh, Kian Agarwal, Vijender Kumar Agrawal, Arun Singh, Sachin Pandey
    Int J Med Sci Public Health. 2012; 1(2): 75-80
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.75-80
    Cited : 5 times [Click to see citing articles]

  • Correlation between obesity and cardio respiratory fitness
    Prabha Setty, BV Padmanabha, BR Doddamani
    Int J Med Sci Public Health. 2013; 2(2): 300-304
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.298-302
    Cited : 5 times [Click to see citing articles]

  • Knowledge, Attitude, and Practices (KAP) study on HIV / AIDS among HIV patients, care givers and general population in north-eastern part of India.
    L P Meena, S K Pandey, M Rai, Anju Bharti, Shyam Sunder
    Int J Med Sci Public Health. 2013; 2(1): 36-42
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.36-42
    Cited : 5 times [Click to see citing articles]

  • Prevalence and clinical characteristics of autism spectrum disorders in school-age children in Taif- KSA
    Ali H.S Al-Zahrani
    Int J Med Sci Public Health. 2013; 2(3): 578-582
    » Abstract & References » doi: 10.5455/ijmsph.2013.160420133
    Cited : 5 times [Click to see citing articles]

  • Electrocardiographic changes during acute mental stress
    Arpana Bhide, Rajasekhar Durgaprasad, Latheef Kasala, Vanajakshamma Velam, Narendra Hulikal
    Int J Med Sci Public Health. 2016; 5(5): 835-838
    » Abstract & References » doi: 10.5455/ijmsph.2016.19082015137
    Cited : 5 times [Click to see citing articles]

  • Importance of cardiac marker enzymes (Aspartate transaminase and troponin I) in acute myocardial infarction: A case-control study from South India
    Vuddandi Prabodh, Deva Prakash, Godi Sudhakar, Yeruva Reddy, Nadella Chowdary, Sripada Desai, Ravi Shekhara
    Int J Med Sci Public Health. 2012; 1(2): 118-120
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.118-120
    Cited : 4 times [Click to see citing articles]

  • Role of HRCT temporal bone in pre operative evaluation of choesteatoma
    Chintan Shah, Pinal Shah, Satish Shah
    Int J Med Sci Public Health. 2014; 3(1): 69-72
    » Abstract & References » doi: 10.5455/ijmsph.2013.031020131
    Cited : 4 times [Click to see citing articles]