E-ISSN 2277-338X | ISSN 2320-4664
 

Case Report 


Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma

Jayasheelan Rachaiah, Niranjan Rachaiah.

Abstract
Asthma is a syndrome characterized by airflow obstruction that varies markedly, both spontaneously and with treatment. There are so many adverse effects of drugs which are used in the management of bronchial asthma in elderly. We report a case of sudden onset paralysis of both lower limbs after treatment of asthma with nebulized β2- agonists. The inappropriate and continuous use of such drugs may cause the hypokalaemic paralysis though life saving many times. hypokalemia is a common adverse effect of β2- agonists but hypokalaemic paralysis of both lower limbs is a rare entity.

Key words: Asthma; β2-Agonists; Hypokalaemia; Paralysis


 
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REFERENCES
1. Tribe RM, Barton JR, Posten L, Burney PGJ. Dietary sodium intake, airway responsiveness and cellular sodium transport. Am J Resp Crit Med. 1994; 149: 1426-33. [DOI via Crossref]   
2. Knox AJ, Britton JR, Tattersfield AE. Effect of sodium transport inhibitors on bronchial reactivity in vivo. Clin Sci (Lond). 1990; 79:325-30.
3. Whyte KF, Reid C, Addis GJ et al. Salbutamol induced hypokalemia: The effect of theophylline alone and in combination with adrenaline. Br J Clin Pharmacol. 1988; 25: 571-8. [DOI via Crossref]   
4. Bodenhamer J, Bergstrom R, Brown D, Gabow P, Marx JA, Lowenstein SR. Frequently nebulized β-agonists for asthma: Effect on serum electrolyte. Ann Emerg Med. 1992; 21: 1337-42. [DOI via Crossref]   
5. Gustafson T, Boman K, Rosenhall L, Sandström T, Wester PO. Skeletal muscle magnesium and potassium in asthmatics treated with oral β2- agonist. Eur Respir J. 1996; 9: 237-40. [DOI via Crossref]   
6. Webb-Johnson DC, Andrews JL. Bronchodialator therapy. N Engl. J Med. 1977; 297: 476 82.
7. Spitzer WO, Suissa S, Ernst P et al. The use of β-agonists and the risk of death and near death from asthma. N Engl J Med. 1992; 326: 501-6. [DOI via Crossref]   
8. Knox AJ, Britton JR, Tattersfield AE. Effect of sodium transport inhibitors on bronchial reactivity in vivo. Clin Sci (Lond). 1990; 79:325-30.
9. Whyte KF, Reid C, Addis GJ, Whitesmith R, Reid JL. Salbutamol induced hypokalemia: The effect of theophylline alone and in combination with adrenaline. Br J Clin Pharmacol. 1988; 25: 571-8. [DOI via Crossref]   
10. Mass AHR, Kofstad J, Siggard-Anderson O. Ionized calcium, sodium, and potassium by Ion selective electrodes. Vol 5. Proceedings of the first meeting of the European working group on Ion selective electrodes. IFCC workshop, Oslo 1983, Copenhagen, Private Press, 1984;654-776.
11. Branes PJ. A New approach to the treatment of asthma. N Engl J Med. 1989; 321: 1517-27. [DOI via Crossref]   
12. DeFronzo RA, Stanton B, Klein-Robbehaar G. Inhibitory effect of epinephrine on renal potassium secretion: a micropunture study. Am J Physiol. 1983; 245:303-11.
13. Diercks DB, Shumaik GM, Harrigan RA, Brady WJ, Chan TC. Electrocardiographic manifestations: electrolyte abnormalities. J Emerg Med. 2004;27(2):153–60. [DOI via Crossref]   
14. Philips PJ, Vedig AE, Jones PL, Chapman MG, Collins M, Edwards JB, et al. Metabolic and cardiovascular side effects of β2 adrenoceptor agonists salbutamol and rimiterol. Br J Clin Pharmacol 1980; 9:

How to Cite this Article
Pubmed Style

Rachaiah J, Rachaiah N. Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma. Int J Med Sci Public Health. 2013; 2(4): 1114-1116. doi:10.5455/ijmsph.2013.030720132


Web Style

Rachaiah J, Rachaiah N. Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma. http://www.ijmsph.com/?mno=40480 [Access: April 21, 2018]. doi:10.5455/ijmsph.2013.030720132


AMA (American Medical Association) Style

Rachaiah J, Rachaiah N. Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma. Int J Med Sci Public Health. 2013; 2(4): 1114-1116. doi:10.5455/ijmsph.2013.030720132



Vancouver/ICMJE Style

Rachaiah J, Rachaiah N. Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma. Int J Med Sci Public Health. (2013), [cited April 21, 2018]; 2(4): 1114-1116. doi:10.5455/ijmsph.2013.030720132



Harvard Style

Rachaiah, J. & Rachaiah, N. (2013) Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma. Int J Med Sci Public Health, 2 (4), 1114-1116. doi:10.5455/ijmsph.2013.030720132



Turabian Style

Rachaiah, Jayasheelan, and Niranjan Rachaiah. 2013. Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma. International Journal of Medical Science and Public Health, 2 (4), 1114-1116. doi:10.5455/ijmsph.2013.030720132



Chicago Style

Rachaiah, Jayasheelan, and Niranjan Rachaiah. "Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma." International Journal of Medical Science and Public Health 2 (2013), 1114-1116. doi:10.5455/ijmsph.2013.030720132



MLA (The Modern Language Association) Style

Rachaiah, Jayasheelan, and Niranjan Rachaiah. "Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma." International Journal of Medical Science and Public Health 2.4 (2013), 1114-1116. Print. doi:10.5455/ijmsph.2013.030720132



APA (American Psychological Association) Style

Rachaiah, J. & Rachaiah, N. (2013) Unusual cause of hypokalemia and paralysis in an elderly patient with Bronchial Asthma. International Journal of Medical Science and Public Health, 2 (4), 1114-1116. doi:10.5455/ijmsph.2013.030720132





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