E-ISSN 2277-338X | ISSN 2320-4664
 

Case Report 


Sugammadex associate persistant bradycardia

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu.

Cited by (5)

Abstract
Sugammadex is a safe selective relaxant binding agent, composed of modified cyclodextrin molecules. It especially has a selectivity for neuromuscular blocking agents (NMBAs) of steroid composition, such as rocuronium and vecuronium. In this paper, we present a case where intravenous (iv) sugammadex has been applied and subsequently persistent bradycardia has developed. A 56-year-old male patient (weight 77 kg, height 163 cm) was scheduled for ureterorenoscopy because of a stone in the upper part of ureter. Preoperative examination showed possible difficult intubation (mallampati 3). There are no known heart diseases and no history of any drug use. The electrocardiography was in normal sinus rhythm, and the blood biochemistry was normal. (WBC: 8.47 K/mm3; Hb: 14.3 g/dL; Na: 135 mEq/L; K: 3.9 mEq/L; BUN: 41 mg/dL; Creatin: 0.69 mg/dL).When the operation ended, We monitored neuromuscular block level with a neuromuscular monitoring device (TOF- Watch S). At the end of the operation, 200 mg sugammadex (Bridion 200 mg/2 mL, MSD) was administered to the patient through iv injection. Approximately 2 minutes following the administration, the patient developed sinusoidal bradycardia (pulse 35 beats/min). We believe that cardiac side effects may be observed following sugammadex administration and that atropine-resistant bradycardia may also develop.

Key words: Sugammadex; Bradycardia; Case Report


 
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This Article Cited By the following articles

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How to Cite this Article
Pubmed Style

Bilgi M, Demirhan A, Akkaya A, Tekelioglu UY, Kocoglu H. Sugammadex associate persistant bradycardia. Int J Med Sci Public Health. 2014; 3(3): 372-374. doi:10.5455/ijmsph.2013.251220131


Web Style

Bilgi M, Demirhan A, Akkaya A, Tekelioglu UY, Kocoglu H. Sugammadex associate persistant bradycardia. http://www.ijmsph.com/?mno=48110 [Access: September 23, 2018]. doi:10.5455/ijmsph.2013.251220131


AMA (American Medical Association) Style

Bilgi M, Demirhan A, Akkaya A, Tekelioglu UY, Kocoglu H. Sugammadex associate persistant bradycardia. Int J Med Sci Public Health. 2014; 3(3): 372-374. doi:10.5455/ijmsph.2013.251220131



Vancouver/ICMJE Style

Bilgi M, Demirhan A, Akkaya A, Tekelioglu UY, Kocoglu H. Sugammadex associate persistant bradycardia. Int J Med Sci Public Health. (2014), [cited September 23, 2018]; 3(3): 372-374. doi:10.5455/ijmsph.2013.251220131



Harvard Style

Bilgi, M., Demirhan, A., Akkaya, A., Tekelioglu, U. Y. & Kocoglu, H. (2014) Sugammadex associate persistant bradycardia. Int J Med Sci Public Health, 3 (3), 372-374. doi:10.5455/ijmsph.2013.251220131



Turabian Style

Bilgi, Murat, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, and Hasan Kocoglu. 2014. Sugammadex associate persistant bradycardia. International Journal of Medical Science and Public Health, 3 (3), 372-374. doi:10.5455/ijmsph.2013.251220131



Chicago Style

Bilgi, Murat, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, and Hasan Kocoglu. "Sugammadex associate persistant bradycardia." International Journal of Medical Science and Public Health 3 (2014), 372-374. doi:10.5455/ijmsph.2013.251220131



MLA (The Modern Language Association) Style

Bilgi, Murat, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, and Hasan Kocoglu. "Sugammadex associate persistant bradycardia." International Journal of Medical Science and Public Health 3.3 (2014), 372-374. Print. doi:10.5455/ijmsph.2013.251220131



APA (American Psychological Association) Style

Bilgi, M., Demirhan, A., Akkaya, A., Tekelioglu, U. Y. & Kocoglu, H. (2014) Sugammadex associate persistant bradycardia. International Journal of Medical Science and Public Health, 3 (3), 372-374. doi:10.5455/ijmsph.2013.251220131





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