Sugammadex associate persistant bradycardia

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu

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Int J Med Sci Public Health. 2014; 3(3): 372-374

doi: 10.5455/ijmsph.2013.251220131

Sugammadex associate persistant bradycardia

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu.

Cited by (11)

Abstract
Sugammadex is a safe selective relaxant binding agent, composed of modified cyclodextrin molecules. It especially has a selectivity for neuromuscular blocking agents (NMBAs) of steroid composition, such as rocuronium and vecuronium. In this paper, we present a case where intravenous (iv) sugammadex has been applied and subsequently persistent bradycardia has developed. A 56-year-old male patient (weight 77 kg, height 163 cm) was scheduled for ureterorenoscopy because of a stone in the upper part of ureter. Preoperative examination showed possible difficult intubation (mallampati 3). There are no known heart diseases and no history of any drug use. The electrocardiography was in normal sinus rhythm, and the blood biochemistry was normal. (WBC: 8.47 K/mm3; Hb: 14.3 g/dL; Na: 135 mEq/L; K: 3.9 mEq/L; BUN: 41 mg/dL; Creatin: 0.69 mg/dL).When the operation ended, We monitored neuromuscular block level with a neuromuscular monitoring device (TOF- Watch S). At the end of the operation, 200 mg sugammadex (Bridion 200 mg/2 mL, MSD) was administered to the patient through iv injection. Approximately 2 minutes following the administration, the patient developed sinusoidal bradycardia (pulse 35 beats/min). We believe that cardiac side effects may be observed following sugammadex administration and that atropine-resistant bradycardia may also develop.

Key words: Sugammadex; Bradycardia; Case Report

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How to Cite this Article

Pubmed Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu. Sugammadex associate persistant bradycardia. Int J Med Sci Public Health. 2014; 3(3): 372-374. doi:10.5455/ijmsph.2013.251220131

Web Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu. Sugammadex associate persistant bradycardia. http://www.ijmsph.com/?mno=48110 [Access: August 29, 2020]. doi:10.5455/ijmsph.2013.251220131

AMA (American Medical Association) Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu. Sugammadex associate persistant bradycardia. Int J Med Sci Public Health. 2014; 3(3): 372-374. doi:10.5455/ijmsph.2013.251220131

Vancouver/ICMJE Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu. Sugammadex associate persistant bradycardia. Int J Med Sci Public Health. (2014), [cited August 29, 2020]; 3(3): 372-374. doi:10.5455/ijmsph.2013.251220131

Harvard Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu (2014) Sugammadex associate persistant bradycardia. Int J Med Sci Public Health, 3 (3), 372-374. doi:10.5455/ijmsph.2013.251220131

Turabian Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu. 2014. Sugammadex associate persistant bradycardia. International Journal of Medical Science and Public Health, 3 (3), 372-374. doi:10.5455/ijmsph.2013.251220131

Chicago Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu. "Sugammadex associate persistant bradycardia." International Journal of Medical Science and Public Health 3 (2014), 372-374. doi:10.5455/ijmsph.2013.251220131

MLA (The Modern Language Association) Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu. "Sugammadex associate persistant bradycardia." International Journal of Medical Science and Public Health 3.3 (2014), 372-374. Print. doi:10.5455/ijmsph.2013.251220131

APA (American Psychological Association) Style

Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu (2014) Sugammadex associate persistant bradycardia. International Journal of Medical Science and Public Health, 3 (3), 372-374. doi:10.5455/ijmsph.2013.251220131

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