International Journal of Medical Science and Public Health

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Int J Med Sci Public Health. 2014; 3(3): 369-371

doi: 10.5455/ijmsph.2014.150120142

Correlation of thrombocytopenia in urban childern with malaria

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor.

Abstract
Background: Malaria, is endemic in Surat, (an industrious city of Gujarat), which is categorised under High risk zone. Malaria affects all blood components and is a true haematological disease. Thrombocytopenia and anaemia are the most frequently malaria associated haematological complications of malaria.

Aims & Objective: To study the occurrence, severity and correlation of Thrombocytopenia in urban children with malaria.

Materials and Methods: A retrospective study was conducted at Surat Municipal Institute Of Medical Education and Research (SMIMER) , Surat Gujarat . The Data of all smear positive and Rapid Diagnostic Test positive malaria cases of age between 1 and 17 year admitted in the Deptt. Of Pediatrics were collected. These patients were further assessed for thrombocytopenia, its severity, its relation with type of malaria and age.

Results: Thrombocytopenia was observed in 233 (74%) cases of Malaria of which P. vivax was in 103 (44%) cases, P. falciparum in 130(56%) cases. Severe thrombocytopenia was observed in 22% and 29% cases of Pv and Pf malaria respectively. Sensitivity of thrombocytopenia in Pv and Pf was 71.53% and 76.92% whereas specificity was 66.67 for both respectively. Sensitivity of thrombocytopenia in Pv increased as the platelet count decreased.

Conclusion: Thrombocytopenia is a frequent overall manifestation of both falciparum and Vivax malaria Severe Thrombocytopenia should alert one to consider a possibility of malaria in children.

Key words: Thrombocytopenia , Plasmodium vivax (Pv), Plasmodium falciparum(Pf) ,Severe malaria

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REFERENCES

1. National Institute of Malaria Research and National Vector Borne Disease Control Programme, Govt. of India.Guidelines for diagnosis and treatment of Malaria 2010. Available form URL: http://nvbdcp.gov.in/Doc/Technical-Guidelines-Malaria-2010.pdf. Accessed on 8 December, 2013.

2. Kaushik J, Gomber S, Deewan P. Clinical and Epidemiological Profiles of Severe Malaria in Children from Delhi, India. J Health Popul Nutr. 2012;30(1):113-116 [DOI via Crossref] [Pubmed] [PMC Free Fulltext]

3. Basu S, Gupta P. Malaria. In: Ghai OP, Gupta P, editors. Textbook of preventive and social Medicine, 3rded. New Delhi: CBS Publishers and Distributors, 2010 : 214-30.

4. Bhandary N, Vikram GS, Shetty H. Thrombocytopenia in malaria: A clinical study. BiomedRes. 2011; 22(4): 489-491.

5. Maina RN, Walsh D, Gaddy C, Hongo G, Waitumbi J, Otieno J, etal. Impact of Plasmodium falciparum infection on haematological parameters in children living in Western Kenya. Malar J. 2010; 9(Suppl 3): S4. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]

6. Aduragbenro DA, Catherine OF, Rachel TK, George OA. Age as a risk factor forthrombocytopenia and anaemia in children treated for acute uncomplicated falciparummalaria. J Vector Borne Dis. 2007; 44: 266-271.

7. Lathia T, Joshi R. Can hematological parameters discriminate malaria from nonmalarious acute febrile illness in the tropics? Indian J Med Sci 2004; 58(6): 239-244. [Pubmed]

8. Gupta N, Bansal S. Study of thrombocytopenia in patients of malaria. TropicalParasitology. 2013;3(1):58-61.

9. Shetty G, Shreedhara K.Thrombocytopenia in children with malaria – A Study fromCoastal Karnataka, India. Asia Pacific J Trop Dis. 2012; 107-109.

10. Colonel KMU, Bhika RD, Khalid S, Khalique-ur-Rehman S, SyesZAS. Severe Thrombocytopenia and prolonged bleeding time in patients with malaria (a clinical study of 162 malaria cases). World Appl Sci J. 2010; 9(5): 484-488.

11. Jamal A, Memon I, Latif F. The association of Plasmodium vivax malaria with thrombocytopenia in febrile children. Pak Paediatr J. 2007; 31(2): 85 -89.

12. Tanwar G, Khatri P. Thrombocytopenia in with special childhood malaria reference to P. vivax monoinfection: A study from Bikaner (Northwestern India). Platelets. 2011;23(3):211-216. [DOI via Crossref] [Pubmed]

13. Metanat M, Mood S. Malaria vivax and severe thrombocytopenia in Iran. Iran J Parasitol. 2010; 5(3): 69-70. [Pubmed] [PMC Free Fulltext]

14. Thapa R, Biswas B, Mallick D, Sardar S, Modak S. Childhood Plasmodium vivax malaria with severe thrombocytopenia and bleeding manifestations. J Pediatr Hematol Oncol. 2009;31:758-759. [DOI via Crossref] [Pubmed]

15. Sharma A, Khanduri U. How benign is benign tertian malaria? JVector Borne Dis. 2009;46: 141-144. [Pubmed]

16. Mahmood A, Yasir M. Thrombocytopenia: a predictor of malaria among febrile patients in Liberia, Infectious Diseases Journal.2008; 14: 41–44.

17. Lathia T, Joshi R. Can hematological parameters discriminate malaria from nonmalarious acute febrile illness in the tropics? Indian Journal of Medical Sciences. 2004; 58 :239–244. [Pubmed]

18. Khan S, Abbas Y. Thrombocytopenia as an Indicator of Malaria in Adult Population. Malar Res Treat. 2012;4: 1-4 [DOI via Crossref] [Pubmed] [PMC Free Fulltext]

How to Cite this Article

Pubmed Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor. Correlation of thrombocytopenia in urban childern with malaria. Int J Med Sci Public Health. 2014; 3(3): 369-371. doi:10.5455/ijmsph.2014.150120142

Web Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor. Correlation of thrombocytopenia in urban childern with malaria. http://www.ijmsph.com/?mno=49383 [Access: February 21, 2019]. doi:10.5455/ijmsph.2014.150120142

AMA (American Medical Association) Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor. Correlation of thrombocytopenia in urban childern with malaria. Int J Med Sci Public Health. 2014; 3(3): 369-371. doi:10.5455/ijmsph.2014.150120142

Vancouver/ICMJE Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor. Correlation of thrombocytopenia in urban childern with malaria. Int J Med Sci Public Health. (2014), [cited February 21, 2019]; 3(3): 369-371. doi:10.5455/ijmsph.2014.150120142

Harvard Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor (2014) Correlation of thrombocytopenia in urban childern with malaria. Int J Med Sci Public Health, 3 (3), 369-371. doi:10.5455/ijmsph.2014.150120142

Turabian Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor. 2014. Correlation of thrombocytopenia in urban childern with malaria. International Journal of Medical Science and Public Health, 3 (3), 369-371. doi:10.5455/ijmsph.2014.150120142

Chicago Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor. "Correlation of thrombocytopenia in urban childern with malaria." International Journal of Medical Science and Public Health 3 (2014), 369-371. doi:10.5455/ijmsph.2014.150120142

MLA (The Modern Language Association) Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor. "Correlation of thrombocytopenia in urban childern with malaria." International Journal of Medical Science and Public Health 3.3 (2014), 369-371. Print. doi:10.5455/ijmsph.2014.150120142

APA (American Psychological Association) Style

Gurudutt Joshi, Nilay Chaudhary, Yogesh Labana, Vimal Tailor (2014) Correlation of thrombocytopenia in urban childern with malaria. International Journal of Medical Science and Public Health, 3 (3), 369-371. doi:10.5455/ijmsph.2014.150120142



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