E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo

Surendra Kumar, Taniya Mehta, Sumitra Nain, Shyam Sunder Pandey, Anil Kumar Gulati, Jyoti Shukla.

Abstract
Background: Transplantation of autologous non-cultured epidermal cell suspension containing melanocytes (ANEM) is one of the well-known surgical options for repigmenting stable vitiligo lesions. The recipient site for transplantation has traditionally been prepared by dermabrasion, liquid N2, or laser resurfacing, which is costly, cumbersome and has risk of scarring.

Objectives: The objectives of this study were to experiment a novel method of repigmenting stable vitiligo lesions by intraepidermal injection of ANEM in the vitiligo lesions.

Materials and Methods: A total of 50 stable vitiligo lesions in 50 patients were included in the study. The prepared ANEM was inoculated intraepidermally in the lesions. Patients were given PUVASOL therapy in post-operative period and followed up 4 weekly for 24 weeks to see repigmentation.

Results: At 24 weeks, pigmentation was seen in 31 (62%) lesions of 50 lesions. It was excellent in 6 (12%), good in 10 (20%), satisfactory in 8 (16%), and poor in 7 (14%) patients. Adverse events were mild and insignificant.

Conclusion: Intraepidermal ANEM inoculation in stable vitiligo lesions is an effective, safe, and cheap dermatosurgical procedure.

Key words: Intralesional, Intraepidermal, Vitiligo, Melanocyte


 
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Pubmed Style

Kumar S, Mehta T, Nain S, Pandey SS, Gulati AK, Shukla J. Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo. Int J Med Sci Public Health. 2019; 8(8): 648-653. doi:10.5455/ijmsph.2019.0515803062019


Web Style

Kumar S, Mehta T, Nain S, Pandey SS, Gulati AK, Shukla J. Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo. http://www.ijmsph.com/?mno=51128 [Access: August 20, 2019]. doi:10.5455/ijmsph.2019.0515803062019


AMA (American Medical Association) Style

Kumar S, Mehta T, Nain S, Pandey SS, Gulati AK, Shukla J. Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo. Int J Med Sci Public Health. 2019; 8(8): 648-653. doi:10.5455/ijmsph.2019.0515803062019



Vancouver/ICMJE Style

Kumar S, Mehta T, Nain S, Pandey SS, Gulati AK, Shukla J. Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo. Int J Med Sci Public Health. (2019), [cited August 20, 2019]; 8(8): 648-653. doi:10.5455/ijmsph.2019.0515803062019



Harvard Style

Kumar, S., Mehta, . T., Nain, . S., Pandey, . S. S., Gulati, . A. K. & Shukla, . J. (2019) Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo. Int J Med Sci Public Health, 8 (8), 648-653. doi:10.5455/ijmsph.2019.0515803062019



Turabian Style

Kumar, Surendra, Taniya Mehta, Sumitra Nain, Shyam Sunder Pandey, Anil Kumar Gulati, and Jyoti Shukla. 2019. Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo. International Journal of Medical Science and Public Health, 8 (8), 648-653. doi:10.5455/ijmsph.2019.0515803062019



Chicago Style

Kumar, Surendra, Taniya Mehta, Sumitra Nain, Shyam Sunder Pandey, Anil Kumar Gulati, and Jyoti Shukla. "Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo." International Journal of Medical Science and Public Health 8 (2019), 648-653. doi:10.5455/ijmsph.2019.0515803062019



MLA (The Modern Language Association) Style

Kumar, Surendra, Taniya Mehta, Sumitra Nain, Shyam Sunder Pandey, Anil Kumar Gulati, and Jyoti Shukla. "Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo." International Journal of Medical Science and Public Health 8.8 (2019), 648-653. Print. doi:10.5455/ijmsph.2019.0515803062019



APA (American Psychological Association) Style

Kumar, S., Mehta, . T., Nain, . S., Pandey, . S. S., Gulati, . A. K. & Shukla, . J. (2019) Intraepidermal injection of autologous non-cultured epidermal cell suspension in lesions of stable vitiligo: A novel method of repigmenting vitiligo. International Journal of Medical Science and Public Health, 8 (8), 648-653. doi:10.5455/ijmsph.2019.0515803062019





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