E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility

Shaista Mushtaq Hamdani, Nazia Quyoom Dar, Ruby Reshi.

Abstract
Background: Central nervous system (CNS) tumors are infrequent tumors comprising <2% of all malignancies. However, a rising global trend in these tumors has been observed over the years with new potential risk factors being identified for brain tumors.

Objective: The aim of the present study is to highlight the histopathological spectrum of brain tumors in a single tertiary care center in our region.

Materials and Methods: This retrospective histopathological analysis of brain tumors was carried out in the Postgraduate Department of Pathology, Government Medical College, Srinagar, Jammu and Kashmir, India, from January 2015 to December 2018. During this period, a total of 117 neurosurgical biopsies were retrieved from the archives of the department. The diagnoses in all the cases were made on histopathological examination of routinely processed tissue. The hematoxylin and eosin (H and E) stained sections in all cases were reviewed by the authors, and diagnosis was confirmed applying the WHO classification 2007. The relative frequency of tumors and the distribution as per age, sex, and location of the lesion were analyzed.

Results: A wide range of histopathological spectrum of CNS tumors was observed and was classified according to the WHO classification system of 2007. The primary CNS tumors were graded from Grade I to Grade 1V. Overall tumors of meninges (41.02%) were the most common entity followed by the astrocytic tumors (35.04%).

Conclusion: The present study helps to provide information regarding the burden of disease in our area. Despite the use of modern imaging technique that helps in provisional diagnosis of disease, histological examination is gold standard in the diagnosis of varied types of brain tumors. Further utility of immunohistochemistry aids in confirmation of the disease.

Key words: Central Nervous System Tumors; Glioma; Meningioma; Histopathology; Immunohistochemistry


 
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Pubmed Style

Hamdani SM, Dar NQ, Reshi R. Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility. Int J Med Sci Public Health. 2019; 8(8): 673-676. doi:10.5455/ijmsph.2019.0616504062019


Web Style

Hamdani SM, Dar NQ, Reshi R. Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility. http://www.ijmsph.com/?mno=51499 [Access: February 16, 2020]. doi:10.5455/ijmsph.2019.0616504062019


AMA (American Medical Association) Style

Hamdani SM, Dar NQ, Reshi R. Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility. Int J Med Sci Public Health. 2019; 8(8): 673-676. doi:10.5455/ijmsph.2019.0616504062019



Vancouver/ICMJE Style

Hamdani SM, Dar NQ, Reshi R. Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility. Int J Med Sci Public Health. (2019), [cited February 16, 2020]; 8(8): 673-676. doi:10.5455/ijmsph.2019.0616504062019



Harvard Style

Hamdani, S. M., Dar, . N. Q. & Reshi, . R. (2019) Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility. Int J Med Sci Public Health, 8 (8), 673-676. doi:10.5455/ijmsph.2019.0616504062019



Turabian Style

Hamdani, Shaista Mushtaq, Nazia Quyoom Dar, and Ruby Reshi. 2019. Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility. International Journal of Medical Science and Public Health, 8 (8), 673-676. doi:10.5455/ijmsph.2019.0616504062019



Chicago Style

Hamdani, Shaista Mushtaq, Nazia Quyoom Dar, and Ruby Reshi. "Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility." International Journal of Medical Science and Public Health 8 (2019), 673-676. doi:10.5455/ijmsph.2019.0616504062019



MLA (The Modern Language Association) Style

Hamdani, Shaista Mushtaq, Nazia Quyoom Dar, and Ruby Reshi. "Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility." International Journal of Medical Science and Public Health 8.8 (2019), 673-676. Print. doi:10.5455/ijmsph.2019.0616504062019



APA (American Psychological Association) Style

Hamdani, S. M., Dar, . N. Q. & Reshi, . R. (2019) Histopathological spectrum of brain tumors: A 4-year retrospective study from a single tertiary care facility. International Journal of Medical Science and Public Health, 8 (8), 673-676. doi:10.5455/ijmsph.2019.0616504062019





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