E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra

Sachin Shivaji Kapse, Shanu Srivastava, Aradhana Mishra.

Abstract
Background: Blood is precious as well as scarce lifesaving medication. Proper screening of transfusion-transmitted infections (TTIs) such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis, and malarial parasite (MP) with appropriate methods is needed to ensure that the donated blood is made innocuous for transfusion.

Objective: The aim of the study was to estimate the prevalence of TTI and their epidemiological aspects in blood donors in a hospital-based blood bank in Nerul, Navi Mumbai.

Materials and Methods: A retrospective study of the total of 4708 donors was carried out from January 2015 to December 2018 year. Screening of HIV was done using the fourth-generation enzyme-linked immunosorbent assay (ELISA) and for hepatitis B surface antigen (HbsAg) and HCV by the third-generation ELISA kit. Testing for syphilis was done with rapid plasma reagin and MP was tested with rapid card test.

Results: Voluntary donors were 4702 (99.9%) while replacement constituted for 6 (0.12%) number of cases. Among 4708 donors, 4079 (96%) were male and 629 (4%) were female. Among 66 (1.4%) transfusion transmitted diseases (TTD)-positive donors, the highest number of donors 28 (42%) belongs to 18–27 years of age group while the lowest 5 (2%) belonged to 48–57 years. Overall prevalence of HIV, HbsAg, HCV, syphilis, and MP was 0.08%, 1.1%, 0.2%, 0.04%, and 0.02%, respectively.

Conclusion: The prevalence of TTD was more in males, in 18–27 age groups, and in voluntary donors. The most common TTI was HBV, followed by HCV, HIV, syphilis, and MP, respectively.

Key words: Human Immunodeficiency Virus; Hepatitis B Surface Antigen; Hepatitis C Virus; Malaria; Syphilis; Transfusion-transmitted Infections


 
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How to Cite this Article
Pubmed Style

Kapse SS, Srivastava S, Mishra A. Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra. Int J Med Sci Public Health. 2019; 8(10): 843-847. doi:10.5455/ijmsph.2019.0720924072019


Web Style

Kapse SS, Srivastava S, Mishra A. Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra. http://www.ijmsph.com/?mno=57515 [Access: October 21, 2019]. doi:10.5455/ijmsph.2019.0720924072019


AMA (American Medical Association) Style

Kapse SS, Srivastava S, Mishra A. Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra. Int J Med Sci Public Health. 2019; 8(10): 843-847. doi:10.5455/ijmsph.2019.0720924072019



Vancouver/ICMJE Style

Kapse SS, Srivastava S, Mishra A. Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra. Int J Med Sci Public Health. (2019), [cited October 21, 2019]; 8(10): 843-847. doi:10.5455/ijmsph.2019.0720924072019



Harvard Style

Kapse, S. S., Srivastava, . S. & Mishra, . A. (2019) Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra. Int J Med Sci Public Health, 8 (10), 843-847. doi:10.5455/ijmsph.2019.0720924072019



Turabian Style

Kapse, Sachin Shivaji, Shanu Srivastava, and Aradhana Mishra. 2019. Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra. International Journal of Medical Science and Public Health, 8 (10), 843-847. doi:10.5455/ijmsph.2019.0720924072019



Chicago Style

Kapse, Sachin Shivaji, Shanu Srivastava, and Aradhana Mishra. "Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra." International Journal of Medical Science and Public Health 8 (2019), 843-847. doi:10.5455/ijmsph.2019.0720924072019



MLA (The Modern Language Association) Style

Kapse, Sachin Shivaji, Shanu Srivastava, and Aradhana Mishra. "Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra." International Journal of Medical Science and Public Health 8.10 (2019), 843-847. Print. doi:10.5455/ijmsph.2019.0720924072019



APA (American Psychological Association) Style

Kapse, S. S., Srivastava, . S. & Mishra, . A. (2019) Seroepidemiology of transfusion-transmitted infections among blood donors at a tertiary care center in Navi Mumbai, Maharashtra. International Journal of Medical Science and Public Health, 8 (10), 843-847. doi:10.5455/ijmsph.2019.0720924072019





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