E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Study of lipid profile in patients of psoriasis with relation to lifestyle factors

Prakash K Kute, Manohar G Muddeshwar, Amol R Sonare.

Abstract
Background: Psoriasis is a chronic inflammatory disease. The chronic inflammation was also observed to be associated with increased risk of cardiovascular episodes as a result of dyslipidemia. Thus, psoriasis and dyslipidemia may share a common causative mechanism. Lifestyle factors such as smoking and alcoholism may further deteriorate the condition.

Objective: The objective of this study was to study the lipid profile pattern in psoriasis with relation to lifestyle factors.

Materials and Methods: This was a cross-sectional study with comparison groups. Fifty diagnosed cases of psoriasis were chosen, out of that 16 were smoker and 12 were alcoholic, and 50 age- and sex-matched healthy normal subjects as controls were also selected for the study. In this study, we measured total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and very LDL cholesterol (VLDL-C) with relation to lifestyle factors, i.e. smoking and alcoholism.

Results: The mean levels of serum total cholesterol, triglycerides, LDL-C, and VLDL-C were 213.5 ± 39.56 mg%, 223.94 ± 34.74 mg%, 136.42 ± 29.1 mg%, and 44.8 ± 6.95 mg% in cases, respectively, and 157.96+ 24.71 mg%, 142.98 ± 21.87 mg%, 80.6 ± 16.79 mg%, and 28.6 ± 4.30 mg% in controls, respectively (P < 0.0001); HDL-C levels were 42.64 ± 6.92 mg% in case and 48.8 ± 8.46 mg% in controls (P = 0.0001). Moreover, levels of serum total cholesterol, triglycerides, LDL-C, and VLDL-C were significantly increased and HDL-C level was significantly decreased in cases with smoking and alcohol habits compared to the cases without smoking and alcoholism. This change indicates dyslipidemia in psoriasis.

Conclusions: Lipid profile may be monitored in the psoriasis cases to minimize the severity of disease and modification in lifestyle factors may be suggested to improve clinical condition.

Key words: Psoriasis; Lipid Profile; Smoking; Alcoholism


 
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How to Cite this Article
Pubmed Style

Kute PK, Muddeshwar MG, Sonare AR. Study of lipid profile in patients of psoriasis with relation to lifestyle factors. Int J Med Sci Public Health. 2019; 8(10): 872-876. doi:10.5455/ijmsph.2019.08223082019


Web Style

Kute PK, Muddeshwar MG, Sonare AR. Study of lipid profile in patients of psoriasis with relation to lifestyle factors. http://www.ijmsph.com/?mno=60171 [Access: October 21, 2019]. doi:10.5455/ijmsph.2019.08223082019


AMA (American Medical Association) Style

Kute PK, Muddeshwar MG, Sonare AR. Study of lipid profile in patients of psoriasis with relation to lifestyle factors. Int J Med Sci Public Health. 2019; 8(10): 872-876. doi:10.5455/ijmsph.2019.08223082019



Vancouver/ICMJE Style

Kute PK, Muddeshwar MG, Sonare AR. Study of lipid profile in patients of psoriasis with relation to lifestyle factors. Int J Med Sci Public Health. (2019), [cited October 21, 2019]; 8(10): 872-876. doi:10.5455/ijmsph.2019.08223082019



Harvard Style

Kute, P. K., Muddeshwar, . M. G. & Sonare, . A. R. (2019) Study of lipid profile in patients of psoriasis with relation to lifestyle factors. Int J Med Sci Public Health, 8 (10), 872-876. doi:10.5455/ijmsph.2019.08223082019



Turabian Style

Kute, Prakash K, Manohar G Muddeshwar, and Amol R Sonare. 2019. Study of lipid profile in patients of psoriasis with relation to lifestyle factors. International Journal of Medical Science and Public Health, 8 (10), 872-876. doi:10.5455/ijmsph.2019.08223082019



Chicago Style

Kute, Prakash K, Manohar G Muddeshwar, and Amol R Sonare. "Study of lipid profile in patients of psoriasis with relation to lifestyle factors." International Journal of Medical Science and Public Health 8 (2019), 872-876. doi:10.5455/ijmsph.2019.08223082019



MLA (The Modern Language Association) Style

Kute, Prakash K, Manohar G Muddeshwar, and Amol R Sonare. "Study of lipid profile in patients of psoriasis with relation to lifestyle factors." International Journal of Medical Science and Public Health 8.10 (2019), 872-876. Print. doi:10.5455/ijmsph.2019.08223082019



APA (American Psychological Association) Style

Kute, P. K., Muddeshwar, . M. G. & Sonare, . A. R. (2019) Study of lipid profile in patients of psoriasis with relation to lifestyle factors. International Journal of Medical Science and Public Health, 8 (10), 872-876. doi:10.5455/ijmsph.2019.08223082019





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