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Original Research 


Toxicological effects of phosphide powder residue in female rats

Ayobola Iyanda.

Cited by (2)

Abstract
Background: Fumigation of cowpea (Vigna unguiculata L. Walp.) using aluminium phosphide is a common practice and contact with this chemical has been demonstrated to result in organ damage, but there is dearth of data on the impact of its powder residue on a mammalian species.

Aims & Objective: The aim of this study is to determine the effect of post-fumigation residue on both liver and kidney of female Wistar rats.

Material and Methods: Eighteen rats were randomly divided into each of the three experimental groups. A group was fed with untreated cowpea and served as control; either of the two other groups was fed phosphide-powder residue contaminated or uncontaminated cowpea. Serum obtained from blood that was collected through retro-orbital bleeding was utilized for biochemical analysis.

Results: While contact with treated but uncontaminated cowpea did not result in either hepatic or renal damage, rats fed phosphide-residue contaminated cowpea exhibited both hepatic and renal damage as the indices (alanine & aspartate aminotransferases, γ- glutamyl transferase, alkaline phosphatase, total protein, albumin, urea, uric acid, creatinine) of study were significantly different (p<0.05) compared with control.

Conclusion: The results of this study suggest that phosphide residue may both nephro and hepatotoxic to female Wistar rats.

Key words: Liver; Kidney; Phosphide Residue; Cowpea


 
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REFERENCES
1. Bergmeyer HU, Scheibe P, Wahlefeld AW. Methods for aspartate and alanine amino transferase. Clin Chem. 1979;125: 1487.
2. McComb RB, Bowers GN, Jr. A study of optimum buffer conditions for measuring alkaline phosphatase activity in human serum. Clin Chem. 1972;18:97.
3. Koch TR, Doumas BT. Bilirubin: Total & conjugated, modified Jendrassik- Grof method. Am Ass Clin Chem. 1982;113.
4. Kingsley CR. The direct biuret method for determination of serum proteins. J Lab Clin Med 28: 1982; 1093-1103.
5. Baeeri M, Shariatpanahi M, Baghaei A, Ghasemi-Niri SF, Mohammadi H, Mohammadirad A, et al. On the benefit of magnetic magnesium nanocarrier in cardiovascular toxicity of aluminum phosphide. Toxicol Ind Health. 2013;29(2):126-35. [DOI via Crossref]   
6. Darbari A, Tandon S, Chaudhary S, Bharadwaj M, Kumar A, Singh GP. Esophageal Injuries Due to Aluminum Phosphide Tablet Poisoning in India. Asian Cardiovasc Thorac Ann. 2008;16(4):298-300. [DOI via Crossref]   
7. Kapoor S, Naik S, Kumar R, Sharma S, Pruthi HS, Varshney S. Benign esophageal stricture following aluminum phosphide poisoning. Indian J Gastroenterol. 2005;24:261-2.
8. Talukdar R, Singal DK, Tandon RK. Aluminum phosphide-induced esophageal stricture. Indian J Gastroenterol. 2006;25:98-9.
9. Madan K, Chalamalasetty SB, Sharma M, Makharia G. Corrosive-like strictures caused by ingestion of aluminum phosphide. Natl Med J India. 2006;19:313-4.
10. Benhalima H, Chaudhry MQ, Mills KA, Price NR. Phosphine resistance in stored-product insects collected from various grain storage facilities in Morocco. J Stored Prod Res. 2004;40:241-249. [DOI via Crossref]   
11. Pimentel MAG, Faroni LRD, Totola MR, Guedes RNC. Phosphine resistance, respiration rate and fitness consequences in stored-product insects. Pest Management Science. 2007;63:876-881. [DOI via Crossref]   
12. Daft JL. Fumigants and related chemicals in foods: review of residue findings, contamination sources, and analytical methods. Sci Total Environ. 1991;100:501-18. [DOI via Crossref]   
13. Mehrpour O, Singh S. Rice tablet poisoning: a major concern in Iranian population. Hum Exp Toxicol. 2010;29(8):701-2. [DOI via Crossref]   
14. Easterwood L, Chaffin MK, Marsh PS, Porter B, Barr C. Phosphine intoxication following oral exposure of horses to aluminum phosphide-treated feed. J Am Vet Med Assoc. 2010;236(4):446-50. [DOI via Crossref]   
15. Bogle RG, Theron P, Brooks P, Dargan PI, Redhead J. Aluminium phosphide poisoning. Emerg Med J. 2006; 23(1): e3. [DOI via Crossref]   
16. Dafour DR. Liver disease. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER and Bruns DE, eds. 4th ed. St. Louis, Missouri: Elsevier Saunders; 2006; 1546-1635.
17. Chefurka W, Kashi KP, Bond EJ. The effect of phosphine on electron transport in mitochondria. Pesticide Biochem Physiol. 1976;6(1):65-84. [DOI via Crossref]   
18. Awofadeji S. Nigeria: Food Poisoning: How Many More Will Have to Die? This Day Live. June 2008. Available from URL: http://www.thisdayonline.com/nview.php?id=117427
19. Commision staff working document. Monitoring of Pesticide Residues in Products of Plant Origin in the European Union, Norway, Iceland & Liechtenstein. May 2005. Available from URL:http://ec.europa.eu/food/fvo/specialreports/pesticide_residues/report_2005_en.pdf

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How to Cite this Article
Pubmed Style

Ayobola Iyanda. Toxicological effects of phosphide powder residue in female rats. Int J Med Sci Public Health. 2013; 2(4): 806-810. doi:10.5455/ijmsph.2013.100620131


Web Style

Ayobola Iyanda. Toxicological effects of phosphide powder residue in female rats. https://www.ijmsph.com/?mno=26023 [Access: April 05, 2022]. doi:10.5455/ijmsph.2013.100620131


AMA (American Medical Association) Style

Ayobola Iyanda. Toxicological effects of phosphide powder residue in female rats. Int J Med Sci Public Health. 2013; 2(4): 806-810. doi:10.5455/ijmsph.2013.100620131



Vancouver/ICMJE Style

Ayobola Iyanda. Toxicological effects of phosphide powder residue in female rats. Int J Med Sci Public Health. (2013), [cited April 05, 2022]; 2(4): 806-810. doi:10.5455/ijmsph.2013.100620131



Harvard Style

Ayobola Iyanda (2013) Toxicological effects of phosphide powder residue in female rats. Int J Med Sci Public Health, 2 (4), 806-810. doi:10.5455/ijmsph.2013.100620131



Turabian Style

Ayobola Iyanda. 2013. Toxicological effects of phosphide powder residue in female rats. International Journal of Medical Science and Public Health, 2 (4), 806-810. doi:10.5455/ijmsph.2013.100620131



Chicago Style

Ayobola Iyanda. "Toxicological effects of phosphide powder residue in female rats." International Journal of Medical Science and Public Health 2 (2013), 806-810. doi:10.5455/ijmsph.2013.100620131



MLA (The Modern Language Association) Style

Ayobola Iyanda. "Toxicological effects of phosphide powder residue in female rats." International Journal of Medical Science and Public Health 2.4 (2013), 806-810. Print. doi:10.5455/ijmsph.2013.100620131



APA (American Psychological Association) Style

Ayobola Iyanda (2013) Toxicological effects of phosphide powder residue in female rats. International Journal of Medical Science and Public Health, 2 (4), 806-810. doi:10.5455/ijmsph.2013.100620131





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