E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Role of squash smear technique in intraoperative diagnosis of CNS tunmors

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal.

Cited by (3)

Abstract
Background: Neurosurgical practice frequently requires intraoperative consultation to optimize surgical procedure. Frozen section and Squash smear cytology can offer the same. As brain tissue is friable & predisposed to show ice crystal artefacts, frozen section is often difficult to interpret. Squash smear examination provides good cytological details to offer diagnosis in most cases except where anatomical correlation is needed. Present study was undertaken to evaluate the efficacy of Squash smear in absence of frozen section facility.

Aims & Objective: To evaluate the value of Squash smear cytology for rapid intraoperative diagnosis in CNS lesions and its correlation with final histomorphological diagnosis.

Material and Methods: Total 35 case of CNS tumours were examined by squash smear technique for cytomorphological analysis followed by histomorphological correlation on paraffin section.

Results: Complete correlation with histomorphological findings was observed in 82.35% of cases. Complete correlation was observed more with glial neoplasm.

Conclusion: Squash smear preparation proved to be a simple, inexpensive and rapid technique for intraoperative consultation of CNS tumours and can be effectively utilized as a diagnostic tool for intraoperative diagnosis in absence of frozen section facility.

Key words: Squash smear cytology, CNS tumors


 
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REFERENCES
1. Kumar V, Abbas AK, Fausto N, Aster JA. Robbins & Cotran Pathologic basis of disease 7th ed. Philadeiphia : Elsevier, 2004.
2. Greig NH, Ries LG, Yancik R, Rapoport SI. Increasing annual incidence of primary malignant brain tumours in elderly. J Natl Cancer Inst 1990;82(20):1621-4. [DOI via Crossref]   
3. Silverberg SG, Delellis RA, Frabe WJ. Principles and practice of Surgical pathology and cytopathology. 3rd edn. New York: Churchil Livingstone. 1997.
4. Kandel ER, Schwartz JH, Jessel TM. Principles of neural science. 4th ed. New York: McGraw-Hill. 2000.
5. Pekmezović Tatjana D, Jarebinski Mirjana S, Pavlović M. Epidemiology of primary central nervous system tumors. Archives of oncology 2002;10(3);177-8. [DOI via Crossref]   
6. Shah AB, Muzumdar GA, Chitale AR, Bhagwati SN. Squash preparation and frozen section in intraoperative diagnosis of central nervous system. Acta. Cytol 1998;42(5):1149-54. [DOI via Crossref]   
7. Suh YL, Koo H, Kim TS, Chi JG, Park SH, Khang SK, et, al. Tumors of the central nervous system in Korea: a multicenter study of 3221 cases. J Neurooncol. 2002;56(3):251-9. [DOI via Crossref]   
8. Andrews NB, Ramesh R, Odijidja T. A preliminary survey of CNS tumours in Tema Ghana. West Afr J Med 2003;22(2):167-72.
9. Statistical report. Primary brain tumors diagnosed in the United States in 2004-2005. Central Brain Tumor Registry of the United States. Available from URL: http://www.cbtrus.org/

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How to Cite this Article
Pubmed Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal. Role of squash smear technique in intraoperative diagnosis of CNS tunmors. Int J Med Sci Public Health. 2013; 2(4): 889-892. doi:10.5455/ijmsph.2013.050720132


Web Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal. Role of squash smear technique in intraoperative diagnosis of CNS tunmors. https://www.ijmsph.com/?mno=37812 [Access: April 05, 2022]. doi:10.5455/ijmsph.2013.050720132


AMA (American Medical Association) Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal. Role of squash smear technique in intraoperative diagnosis of CNS tunmors. Int J Med Sci Public Health. 2013; 2(4): 889-892. doi:10.5455/ijmsph.2013.050720132



Vancouver/ICMJE Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal. Role of squash smear technique in intraoperative diagnosis of CNS tunmors. Int J Med Sci Public Health. (2013), [cited April 05, 2022]; 2(4): 889-892. doi:10.5455/ijmsph.2013.050720132



Harvard Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal (2013) Role of squash smear technique in intraoperative diagnosis of CNS tunmors. Int J Med Sci Public Health, 2 (4), 889-892. doi:10.5455/ijmsph.2013.050720132



Turabian Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal. 2013. Role of squash smear technique in intraoperative diagnosis of CNS tunmors. International Journal of Medical Science and Public Health, 2 (4), 889-892. doi:10.5455/ijmsph.2013.050720132



Chicago Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal. "Role of squash smear technique in intraoperative diagnosis of CNS tunmors." International Journal of Medical Science and Public Health 2 (2013), 889-892. doi:10.5455/ijmsph.2013.050720132



MLA (The Modern Language Association) Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal. "Role of squash smear technique in intraoperative diagnosis of CNS tunmors." International Journal of Medical Science and Public Health 2.4 (2013), 889-892. Print. doi:10.5455/ijmsph.2013.050720132



APA (American Psychological Association) Style

Bharti Jha, Viral Patel, Komal Patel, Anshul Agarwal (2013) Role of squash smear technique in intraoperative diagnosis of CNS tunmors. International Journal of Medical Science and Public Health, 2 (4), 889-892. doi:10.5455/ijmsph.2013.050720132





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