E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Species distribution and antifungal susceptibility profile of Candida isolated from urine samples

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur.

Abstract
Background: Candiduria is a common finding in hospitalized patients. The isolation of Candida from urine is challenging for both clinician and microbiologist as to whether the candiduria represents colonization or, lower or upper urinary tract infection including ascending pyelonephritis and renal candidiasis with sepsis. Although Candida albicans is the major cause of candiduria, non-albicans Candida (NAC) has emerged as an important opportunist pathogen. The NAC spp. are not only well adapted to the urinary tract but also are difficult to eradicate than C. albicans.

Aims & Objective: The present study aimed to determine the clinico-mycological profile of candiduria in a tertiary care hospital.

Material and Methods: A total of 218 Candida spp. isolated from urine samples were included in the study. Speciation of Candida was done by conventional methods and colony colour on HICHROM Candida agar. Antifungal susceptibility testing of the isolates was performed by disc diffusion method on glucose methylene Mueller- Hinton agar (GM-MH).
Results: In both the sexes maximum patients belong to age group >50 years. Urinary catheterization, use of broad spectrum antibiotics and diabetes mellitus were the major risks. Isolation of NAC spp. was more. Maximum resistance was seen to fluconazole.

Conclusion: The shift towards the NAC spp. as the causative agent of candiduria has generated the concern. Since several NAC spp. are inherently resistant to common antifungal agents, the rapid identification of Candida isolates upto species level along with its in-vitro antifungal susceptibility pattern is important for treatment and management of candiduria.

Key words: Antifungal Susceptibility; Fluconazole; Non- Albicans Candida Species; Candida Albicans


 
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How to Cite this Article
Pubmed Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur. Species distribution and antifungal susceptibility profile of Candida isolated from urine samples. Int J Med Sci Public Health. 2013; 2(4): 893-896. doi:10.5455/ijmsph.2013.050720133


Web Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur. Species distribution and antifungal susceptibility profile of Candida isolated from urine samples. https://www.ijmsph.com/?mno=38048 [Access: April 05, 2022]. doi:10.5455/ijmsph.2013.050720133


AMA (American Medical Association) Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur. Species distribution and antifungal susceptibility profile of Candida isolated from urine samples. Int J Med Sci Public Health. 2013; 2(4): 893-896. doi:10.5455/ijmsph.2013.050720133



Vancouver/ICMJE Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur. Species distribution and antifungal susceptibility profile of Candida isolated from urine samples. Int J Med Sci Public Health. (2013), [cited April 05, 2022]; 2(4): 893-896. doi:10.5455/ijmsph.2013.050720133



Harvard Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur (2013) Species distribution and antifungal susceptibility profile of Candida isolated from urine samples. Int J Med Sci Public Health, 2 (4), 893-896. doi:10.5455/ijmsph.2013.050720133



Turabian Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur. 2013. Species distribution and antifungal susceptibility profile of Candida isolated from urine samples. International Journal of Medical Science and Public Health, 2 (4), 893-896. doi:10.5455/ijmsph.2013.050720133



Chicago Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur. "Species distribution and antifungal susceptibility profile of Candida isolated from urine samples." International Journal of Medical Science and Public Health 2 (2013), 893-896. doi:10.5455/ijmsph.2013.050720133



MLA (The Modern Language Association) Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur. "Species distribution and antifungal susceptibility profile of Candida isolated from urine samples." International Journal of Medical Science and Public Health 2.4 (2013), 893-896. Print. doi:10.5455/ijmsph.2013.050720133



APA (American Psychological Association) Style

Omprakash Bobade, Mahesh Waghmare, Pramod Chhabrani, Iqbal Kaur (2013) Species distribution and antifungal susceptibility profile of Candida isolated from urine samples. International Journal of Medical Science and Public Health, 2 (4), 893-896. doi:10.5455/ijmsph.2013.050720133





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