Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases

Vasudha Mahendra Bhagat; Peeyush kumar Saini; Hemali Jayantilal Tailor; Reena Balvant bhai Dudhat; Amita Ramesh bhai Patel; Jigna Pravin chandra Modi

doi:10.5455/ijmsph.2013.090720133

2021, Vol: 10, Issue: 2

10 / 2Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

« Previous Article

Original Research

Int J Med Sci Public Health. 2013; 2(4): 971-974

doi: 10.5455/ijmsph.2013.090720133

Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi.

Abstract
Background: Cancers of the upper aero-digestive tract (UADT) constitute 3.5-4% of all malignancies. Majority of cases
are squamous cell carcinomas which are related with various epidemiologic factors.

Aims & Objective: The objective of this study is to know the histopathological spectrum of tumours of UADT.

Material and Methods: This study comprises of 156 cases of histopathological diagnosed tumours of upper aero
digestive tract who attended new civil hospital, government medical college, Surat, from August 2010 to august 2012.
All prospective and neoplastic cases were included and retrospective and non- neoplastic cases were excluded. Routine
paraffin sectioning and staining was done and immunohistochemistry was applied when required.

Results: Out of total 156 cases of UADT, 129 malignant, 19 cases benign and 8 were carcinoma in-situ cases. In
malignant cases, 124 (96.00%) cases of carcinomas, 1 (0.80%) case of sarcoma, 2 (1.60%) cases of melanoma, and 2
(1.60%) cases were of lymphomas. Most common site of carcinoma was oral cavity (tongue). Most common carcinoma
was Squamous cell carcinoma. Most common site of SCC was hypo pharynx (pyriform Fossa), followed by oral cavity
(tongue) and larynx (supra glottis). In benign tumours, most common site was nasal cavity (7 cases) and common
varieties were Angiofibroma and Capillary Haemangioma.

Conclusion: Tumours of UADT are predominant in males affecting older age group. People with tobacco chewing,
smoking, alcoholism, poor socioeconomic background, mixed diet and poor oral hygiene are more vulnerable.

Key words: Upper aero digestive tract tumours, Squamous cell carcinoma, Oral cavity.

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Vasudha Mahendra Bhagat Articles by Peeyush kumar Saini Articles by Hemali Jayantilal Tailor Articles by Reena Balvant bhai Dudhat Articles by Amita Ramesh bhai Patel Articles by Jigna Pravin chandra Modi
	on Google
	on Google Scholar

REFERENCES

1. Muir C, Weiland L. Upper aerodigestive tract cancers. Cancer 1995;75(1 Suppl):147-53.

2. Cho KJ, Khang SK, Lee SS, Koh JS, Chung JH, Lee YS, et al. Cancers of the Upper Aero digestive Tract in Korea. J Korean Med Sci. 2002;17(1):18-22.

3. Hammer JE. Aetiology and epidemiology of oral cancer. In: Carl W, Sakok K, (eds). Cancer and the oral cavity. Chicago: Quintessence Publishing Co. 1986.

4. Zygogianni AG, Kyrgias G, Karakitsos P, Psyrri A, Kouvaris J, Kelekis N, et al. Oral squamous cell cancer: early detection and the role of alcohol and smoking. Head Neck Oncol. 2011;3:2. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]

5. Skarsgard DP, Groome PA, Mackillop WJ, Zhou S, Rothwell D, Dixon PF, et al. Cancers of the upper aero digestive tract in Ontario, Canada, and the United States. Cancer. 2000;88(7):1728-38. [DOI via Crossref]

6. Sajid M, Singh JB, Ali S, Chanda N, Ahmed S, Ahmed M. Cancers of upper aerodigestive tract in Kashmir a clinicopathologic study. JK Practioners. 2004;11(1):17-20.

7. Franceschi S, Talamini R, Barra S, BarÃƒÂ³n AE, Negri E, Bidoli E, et al. Smoking and drinking in relation to the cancers of oral cavity, pharynx, larynx and esophagus in northern Italy. Cancer Res. 1990;50(20):6502-7.

8. Thakur BS. Oral and oropharyngeal tumours, clinicopathological study of 243 tumours (1991-1997), Karnataka. Karnataka University. 1998.

9. Sharma RN. Oral carcinoma Ã¢Â€Â“A clinical study of 122 cases. J Indian Med Assoc. 1964;43:263-8.

10. 10 Mehrotra R, Pandya S, Chaudhary AK, Kumar M, Singh M. Prevalence of oral premalignant and malignant lesions at a tertiary level hospital in Allahabad, India, Asian Pac J Cancer Prev. 2008;9(2):263-5.

11. Dias GS, Almeida AP. A histological and clinical study on oral cancers, descriptive analysis of 365 cases. Med Oral Patol Oral Cir Bucal. 2007;12(7):E474-8.

12. Khandekar SP, Bagday PS, Tiwari RR. Oral cancers and some epidemiological factors. A hospital based study. Indian J Community Med. 2006;31(3):157-9.

13. Balaram P, Sridhar H, Rajkumar T, Vaccarella S, Herrero R, Nandakumar A, et al. Oral cancers in southern India: The influence of smoking , drinking, tobacco chewing, and oral hygiene, Int J Cancer. 2002;98(3):440-5.

14. Notani PN, Jayant K. Role of diet in tumours of upper aerodigestive tract cancers. Nutr Cancer. 1987;10(1-2): 103-13.

15. Chainani-Wu N. Diet and oral, pharyngeal and esopharyngeal cancer. Nutr Cancer. 2002; 44(2):104-26. [DOI via Crossref] [Pubmed]

16. Behnaud F, Torabian, Zargaram M. Relationship between oral poor hygiene and broken teeth with oral tongue squamous cell carcinoma. Acta Medica Iran. 2011;49(3):159-62.

17. Kingdom TT, Kaplan MJ. Mucosal melanoma of the nasal cavity and paranasal sinuses. Head Neck. 1995;17(3):184-9. [DOI via Crossref]

18. De Matos P, Tyler DS, Seigler HF. Malignant melanoma of the mucous membranes: a review of 119 cases. Ann Surg Oncol. 1998;5(8):733-42. [DOI via Crossref]

How to Cite this Article

Pubmed Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. Int J Med Sci Public Health. 2013; 2(4): 971-974. doi:10.5455/ijmsph.2013.090720133

Web Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. https://www.ijmsph.com/?mno=40359 [Access: April 05, 2022]. doi:10.5455/ijmsph.2013.090720133

AMA (American Medical Association) Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. Int J Med Sci Public Health. 2013; 2(4): 971-974. doi:10.5455/ijmsph.2013.090720133

Vancouver/ICMJE Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. Int J Med Sci Public Health. (2013), [cited April 05, 2022]; 2(4): 971-974. doi:10.5455/ijmsph.2013.090720133

Harvard Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi (2013) Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. Int J Med Sci Public Health, 2 (4), 971-974. doi:10.5455/ijmsph.2013.090720133

Turabian Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi. 2013. Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. International Journal of Medical Science and Public Health, 2 (4), 971-974. doi:10.5455/ijmsph.2013.090720133

Chicago Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi. "Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases." International Journal of Medical Science and Public Health 2 (2013), 971-974. doi:10.5455/ijmsph.2013.090720133

MLA (The Modern Language Association) Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi. "Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases." International Journal of Medical Science and Public Health 2.4 (2013), 971-974. Print. doi:10.5455/ijmsph.2013.090720133

APA (American Psychological Association) Style

Vasudha Mahendra Bhagat, Peeyush kumar Saini, Hemali Jayantilal Tailor, Reena Balvant bhai Dudhat, Amita Ramesh bhai Patel, Jigna Pravin chandra Modi (2013) Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases. International Journal of Medical Science and Public Health, 2 (4), 971-974. doi:10.5455/ijmsph.2013.090720133

Authors retains the copyright of the manuscript/s published by them in this journal.

Copyright © 2022 International Journal of Medical Science and Public Health All Rights Reserved. Subject to change without notice from or liability to International Journal of Medical Science and Public Health. For best results, please use Internet Explorer or Google Chrome	Contact Information Publisher publisherijmsph@gmail.com Editorial query editorijmsph1@gmail.com MOB - 8780040272

Contact Information

How to cite this article